腹腔注射硫代葡萄糖金对鸡（家鸡）生长、食物消耗及金在其各器官中蓄积的影响。

The effect of intraperitoneally administered gold thioglucose on growth, food consumption and accumulation of gold in various organs of the chicken (Gallus domesticus).

Karasawa Y, Sugawa-Katayama Y, Danbara H

Laboratory of Animal Nutrition and Feed Science, Faculty of Agriculture, Shinshu University, Nagano-ken, Japan.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1988;90(2):461-4.

Abstract

Gold thioglucose (GTG) was intraperitoneally injected into 10-day-old male and female chickens in a dose of 0, 0.2, 0.4 or 0.8 mg per gram of body wt. 2. Mortality of the GTG-injected chickens was 100% and 25% for doses of 0.8 and 0.4 mg/gBW respectively, in both sexes and 25% for a dose of 0.2 mg in females, which were all found within 14.5 hr after the GTG treatment. 3. Body weight gain, food consumption and food efficiency of surviving chickens for 23 days after the GTG injection were not affected by GTG in spite of dose level. 4. Gold detected in blood, heart, liver, gallbladder, spleen, proventriculus, gizzard, duodenum, kidney, pectoral muscle, small intestine, lung and brain of the dead chickens accumulated most highly in heart and followed by spleen, but in the surviving chicken a little gold was only found in liver, spleen and kidney of some GTG-treated chickens.

摘要

将硫代葡萄糖金（GTG）以每克体重0、0.2、0.4或0.8毫克的剂量腹腔注射到10日龄的雄性和雌性鸡中。2. 注射GTG的鸡，剂量为0.8毫克/克体重时死亡率为100%，0.4毫克/克体重时死亡率为25%，两性皆是如此；雌性鸡剂量为0.2毫克时死亡率为25%，这些死亡均在GTG处理后14.5小时内出现。3. GTG注射后存活23天的鸡的体重增加、食物消耗和食物效率，无论剂量水平如何，均不受GTG影响。4. 在死亡鸡的血液、心脏、肝脏、胆囊、脾脏、腺胃、肌胃、十二指肠、肾脏、胸肌、小肠、肺和大脑中检测到的金，在心脏中积累最多，其次是脾脏，但在存活鸡中，仅在一些接受GTG处理的鸡的肝脏、脾脏和肾脏中发现少量金。