Obara Piotr, Loening Andreas, Taviani Valentina, Iagaru Andrei, Hargreaves Brian A, Vasanawala Shreyas
Stanford University, 300 Pastuer Drive, Stanford, CA 94305, United States.
Stanford University, Lucas Center for Imaging, 1201 Welch Rd, Stanford, CA 94305, United States.
Clin Imaging. 2018 Mar-Apr;48:62-68. doi: 10.1016/j.clinimag.2017.09.016. Epub 2017 Sep 29.
Evaluate MR protocol for PET-MR including coronal DWI (cDWI), fat-suppressed T2 (T2w), and gadofosveset-enhanced T1 (CE).
18 patients underwent same-day PET-CT and PET-MR. Image quality and performance of each sequence, and combination of all three sequences, was evaluated with respect to PET-CT.
Lesion conspicuity was best on cDWI, while delineation was best on CE. Considering all three sequences combined, both readers showed good sensitivity and specificity (>80%). Relative sensitivity was highest on CE and lowest on T2w.
Whole-body MR performed well in detecting malignant lesions compared to PET-CT. CE showed overall highest performance.
评估用于PET-MR的磁共振成像（MR）方案，包括冠状面扩散加权成像（cDWI）、脂肪抑制T2加权成像（T2w）和钆塞酸二钠增强T1加权成像（CE）。
18例患者在同一天接受了PET-CT和PET-MR检查。根据PET-CT评估每个序列以及所有三个序列组合的图像质量和性能。
cDWI上病变的显示效果最佳，而CE上病变的勾画效果最佳。综合考虑所有三个序列，两位阅片者均显示出良好的敏感性和特异性（>80%）。相对敏感性在CE上最高，在T2w上最低。
与PET-CT相比，全身MR在检测恶性病变方面表现良好。CE总体表现最佳。
