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一起由 GII.P16-GII.2 诺如病毒引起的急性胃肠炎暴发,与中国连云港一家幼儿园空调机组通过空气传播有关。

An acute gastroenteritis outbreak caused by GII.P16-GII.2 norovirus associated with airborne transmission via the air conditioning unit in a kindergarten in Lianyungang, China.

机构信息

Lianyungang Municipal Center for Disease Control and Prevention, Lianyungang, Jiangsu 222003, China.

Haizhou District Center for Disease Control and Prevention, Lianyungang, Jiangsu, China.

出版信息

Int J Infect Dis. 2017 Dec;65:81-84. doi: 10.1016/j.ijid.2017.10.003. Epub 2017 Oct 12.

DOI:10.1016/j.ijid.2017.10.003
PMID:29031606
Abstract

Noroviruses are a common cause of acute gastroenteritis outbreaks in institutions including schools and kindergartens around the world. An outbreak caused by GII.P16-GII.2 norovirus in a kindergarten in Lianyungang, Jiangsu Province, China is reported here. An epidemiological investigation was conducted, and pathogen detection was performed. The descriptive analysis indicated that this outbreak in middle class 1 had a point source. Twenty cases of acute gastroenteritis occurred in this class within a period of 8.5h; the attack rate was 52.6% (20/38). Airborne transmission via the air conditioning unit in a confined restroom could have played a critical role in this outbreak. Sequence analysis of GII-positive samples confirmed that the norovirus GII.P16-GII.2 variant was the etiological agent of this outbreak.

摘要

诺如病毒是导致包括学校和幼儿园在内的全球各类机构暴发急性肠胃炎的常见病原体。本研究报告了一起发生在中国江苏省连云港市某幼儿园的由 GII.P16-GII.2 诺如病毒引起的暴发疫情。进行了流行病学调查和病原体检测。描述性分析表明,该起暴发疫情发生在 1 个中班,具有共同暴露源,在 8.5h 内,该班共 20 名学生罹患急性肠胃炎,罹患率为 52.6%(20/38)。空调设备在封闭的卫生间内通过空气传播可能在此次暴发疫情中发挥了关键作用。对 GII 阳性样本的序列分析证实,该起暴发疫情的病原体是诺如病毒 GII.P16-GII.2 变异株。

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