Miami Veterans Administration Medical Center, USA; Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, Miami, FL, USA.
Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA.
Ocul Surf. 2018 Jan;16(1):31-44. doi: 10.1016/j.jtos.2017.10.001. Epub 2017 Oct 12.
Dry eye is a common, multifactorial disease currently diagnosed by a combination of symptoms and signs. Its epidemiology and clinical presentation have many similarities with neuropathic pain outside the eye. This review highlights the similarities between dry eye and neuropathic pain, focusing on clinical features, somatosensory function, and underlying pathophysiology. Implications of these similarities on the diagnosis and treatment of dry eye are discussed.
干眼症是一种常见的多因素疾病,目前通过症状和体征的组合来诊断。其流行病学和临床表现与眼外神经病理性疼痛有许多相似之处。本综述强调了干眼症和神经病理性疼痛之间的相似性,重点讨论了临床特征、躯体感觉功能和潜在的病理生理学。讨论了这些相似性对干眼症诊断和治疗的影响。