Takahashi Yoshiaki, Yamashita Toru, Morihara Ryuta, Nakano Yumiko, Sato Kota, Takemoto Mami, Hishikawa Nozomi, Ohta Yasuyuki, Hayata Kei, Masuyama Hisashi, Okamura Tomoka, Washio Yosuke, Abe Koji
Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Japan.
Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Japan.
Intern Med. 2017 Dec 15;56(24):3361-3364. doi: 10.2169/internalmedicine.8636-16. Epub 2017 Oct 16.
We herein report the case of a 46-year-old pregnant woman with anti-muscle specific kinase (MuSK) antibody-positive myasthenia gravis (MG) who showed pregnancy-induced hypertension and developed respiratory failure at 30 weeks and 5 days of pregnancy, and who underwent an emergency caesarean section (CS). Her MG symptoms gradually improved in the subsequent weeks. The premature baby with positive MuSK antibodies was successfully delivered, but the male baby required temporary artificial ventilation. However, his condition also gradually improved over time. The present case suggests that an emergency CS could rescue both the mother, who was in critical condition, and the prematurely born baby, even when suffering from acute respiratory insufficiency.
我们在此报告一例46岁的抗肌肉特异性激酶（MuSK）抗体阳性重症肌无力（MG）孕妇病例，该孕妇出现妊娠高血压，在妊娠30周零5天时发生呼吸衰竭，并接受了紧急剖宫产（CS）。在随后的几周里，她的重症肌无力症状逐渐改善。携带MuSK抗体阳性的早产儿成功分娩，但男婴需要临时人工通气。然而，随着时间的推移，他的病情也逐渐好转。本病例表明，即使母亲和早产婴儿患有急性呼吸功能不全，紧急剖宫产也可以挽救处于危急状态的母亲和早产婴儿。
