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本文引用的文献

1
Allergic sensitization prevalence in a children and adolescent population of northeastern Greece region.希腊东北部地区儿童和青少年群体中的过敏致敏患病率。
Int J Pediatr Otorhinolaryngol. 2016 Oct;89:33-7. doi: 10.1016/j.ijporl.2016.07.027. Epub 2016 Jul 25.
2
Diagnostic accuracy of skin-prick testing for allergic rhinitis: a systematic review and meta-analysis.皮肤点刺试验诊断变应性鼻炎的准确性:一项系统评价和Meta分析
Allergy Asthma Clin Immunol. 2016 Apr 27;12:20. doi: 10.1186/s13223-016-0126-0. eCollection 2016.
3
Aeroallergens in West Crete, Greece: A five year (2010-2014) aerobiological study.希腊克里特岛西部的空气过敏原:一项为期五年(2010 - 2014年)的空气生物学研究。
Eur Arch Otorhinolaryngol. 2016 Jul;273(7):1943-9. doi: 10.1007/s00405-016-3973-x. Epub 2016 Mar 12.
4
Primary school children often underestimate their nasal obstruction.小学生常常低估自己的鼻塞问题。
Rhinology. 2016 Jun;54(2):164-9. doi: 10.4193/Rhino15.120.
5
Alternaria and Cladosporium calendar of Western Thrace: Relationship with allergic rhinitis symptoms.西色雷斯链格孢属和枝孢属日历:与变应性鼻炎症状的关系
Laryngoscope. 2016 Feb;126(2):E51-6. doi: 10.1002/lary.25594. Epub 2015 Sep 15.
6
The clinical significance of the pollen calendar of the Western Thrace/northeast Greece region in allergic rhinitis.希腊西部色雷斯/希腊东北部地区花粉日历在变应性鼻炎中的临床意义。
Int Forum Allergy Rhinol. 2015 Dec;5(12):1156-63. doi: 10.1002/alr.21623. Epub 2015 Aug 8.
7
Predictors of quality of life improvement in allergic rhinitis patients after sublingual immunotherapy.舌下免疫治疗后变应性鼻炎患者生活质量改善的预测因素
Ann Otol Rhinol Laryngol. 2015 Jun;124(6):430-6. doi: 10.1177/0003489414565001. Epub 2014 Dec 23.
8
Paediatric rhinitis: position paper of the European Academy of Allergy and Clinical Immunology.儿童鼻炎:欧洲过敏与临床免疫学会立场文件。
Allergy. 2013 Sep;68(9):1102-16. doi: 10.1111/all.12235. Epub 2013 Aug 19.
9
Olfactory dysfunction and asthma as risk factors for poor quality of life in upper airway diseases.嗅觉功能障碍和哮喘是上呼吸道疾病生活质量下降的危险因素。
Am J Rhinol Allergy. 2013 Jul-Aug;27(4):293-8. doi: 10.2500/ajra.2013.27.3903.
10
Comparative analysis of allergic rhinitis in children and adults.儿童与成人变应性鼻炎的对比分析。
Curr Allergy Asthma Rep. 2013 Apr;13(2):142-51. doi: 10.1007/s11882-012-0331-y.

变应性鼻炎患儿的症状模式。

Symptomatology Patterns in Children with Allergic Rhinitis.

机构信息

Department of Otorhinolaryngology, Medical School, Democritus University of Thrace, Alexandroupolis, Evros, Greece.

Laboratory of Informatics, Medical School, Democritus University of Thrace, Alexandroupolis, Evros, Greece.

出版信息

Med Sci Monit. 2017 Oct 16;23:4939-4946. doi: 10.12659/msm.903136.

DOI:10.12659/msm.903136
PMID:29033449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5654957/
Abstract

BACKGROUND Although allergic rhinitis (AR) is recognized as a growing global health disease with considerable importance for patients' lives, especially among children and adolescents, there is a lack of population studies concerning symptomatology patterns of the disease. The present study aimed to explore symptoms prevalence among school-aged children, to detect any correlation between allergen sensitivities with symptomatology patterns, and, finally, to evaluate the association of the sensitivity grade score with symptoms severity or seasonality. MATERIAL AND METHODS This was a cross-sectional, observational study in a childhood population. The first stage included recruitment of children and parental-completed questionnaires. The second stage included skin-prick tests for the most common allergens. Severity of symptoms was self-evaluated using a scale that ranged from "0" (no symptoms), "1" (mild), and "2" (moderate-to-severe). AR was classified as seasonal (SAR) or perennial (PAR). RESULTS The most frequent symptoms were reported for nasal obstruction, sneezing, and rhinorrhea. All nasal symptoms were significantly more profound among children with HDM sensitivity. However, more symptoms, not only nasal, but also ocular and general ones, were detected among patients with grass pollen sensitivity. Patients with PAR reported more severe symptoms. SAR was associated with mild disease. Finally, the sensitivity grade score was significantly correlated with symptom severity. CONCLUSIONS Our results suggest that allergen sensitivity may be correlated with symptomatology patterns among children who have allergic rhinitis.

摘要

背景

尽管变应性鼻炎(AR)被认为是一种日益严重的全球性健康疾病,对患者的生活,尤其是儿童和青少年的生活有很大影响,但目前缺乏有关该疾病症状模式的人群研究。本研究旨在探讨学龄儿童的症状流行情况,检测过敏原敏感性与症状模式之间的任何相关性,并最终评估敏感性分级评分与症状严重程度或季节性之间的关联。

材料和方法

这是一项在儿童人群中进行的横断面、观察性研究。第一阶段包括招募儿童和家长完成问卷。第二阶段包括对最常见过敏原进行皮肤点刺试验。症状严重程度采用从“0”(无症状)、“1”(轻度)和“2”(中重度)的量表进行自我评估。AR 分为季节性(SAR)或常年性(PAR)。

结果

报告最常见的症状是鼻塞、打喷嚏和流涕。在对 HDM 敏感的儿童中,所有鼻部症状均明显更严重。然而,在对草花粉敏感的患者中,不仅鼻部症状,而且眼部和全身症状也更多。患有 PAR 的患者报告的症状更严重。SAR 与轻度疾病相关。最后,敏感性分级评分与症状严重程度显著相关。

结论

我们的结果表明,过敏原敏感性可能与患有变应性鼻炎的儿童的症状模式相关。