Suppr超能文献

急性肺血栓栓塞症的外科取栓术

Surgical Embolectomy for Acute Pulmonary Thromboembolism.

作者信息

Fukuda Ikuo, Daitoku Kazuyuki

机构信息

Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.

出版信息

Ann Vasc Dis. 2017 Jun 25;10(2):107-114. doi: 10.3400/avd.ra.17-00038.

Abstract

Acute pulmonary thromboembolism is a catastrophic event, especially for hospitalized patients. The prognosis of pulmonary thromboembolism depends on the degree of pulmonary arterial occlusion. The mortality of massive pulmonary embolism is reportedly as high as 25% without cardiopulmonary arrest and 65% with cardiopulmonary arrest. In patients with unstable hemodynamics due to pulmonary thromboembolism, surgical pulmonary embolectomy is indicated for patients with a contraindication to thrombolysis, failed catheter therapy, or failed thrombolysis. Thrombolytic therapy adds an additional burden on patients who are at risk of potential hemorrhagic complications. It is also indicated if patients are already on a veno-arterial extra-corporate membrane oxygenator for circulatory collapse or cardiopulmonary arrest. The outcome for patients who require cardiopulmonary resuscitation for longer than 30 minutes is poor. Therefore, early triage for massive and sub-massive pulmonary embolism is crucial. A team approach including a cardiovascular surgeon may be effective to save critically ill patients. Prompt removal of emboli reduces the right ventricular load with quick recovery of cardiopulmonary function in the early postoperative period. A recent series reported excellent results, with in-hospital mortality of less than 10%. Surgical pulmonary embolectomy is an effective, safe, and easy procedure to save critical patients due to pulmonary thromboembolism.

摘要

急性肺血栓栓塞是一种灾难性事件,对住院患者而言尤是如此。肺血栓栓塞的预后取决于肺动脉阻塞程度。据报道,大面积肺栓塞在无心肺骤停时的死亡率高达25%,在有心肺骤停时则为65%。对于因肺血栓栓塞导致血流动力学不稳定的患者,若存在溶栓禁忌证、导管治疗失败或溶栓失败,应行外科肺动脉血栓切除术。溶栓治疗会给有潜在出血并发症风险的患者增加额外负担。若患者已因循环衰竭或心肺骤停而使用静脉-动脉体外膜肺氧合,也可进行溶栓治疗。需要心肺复苏超过30分钟的患者预后较差。因此,对大面积和次大面积肺栓塞进行早期分诊至关重要。包括心血管外科医生在内的团队协作方法可能对挽救重症患者有效。及时清除栓子可降低右心室负荷,并使术后早期心肺功能快速恢复。最近的一系列报道显示效果良好,住院死亡率低于10%。外科肺动脉血栓切除术是挽救因肺血栓栓塞导致的重症患者的一种有效、安全且简便的手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71cd/5579785/71104a5c1cdb/avd-10-2-ra.17-00038-figure01.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验