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用于研究抗真菌活性的蛋白质磷酸化对应物制备数据集,该抗真菌活性对抗真菌剂呈剂量依赖性敏感。

Dataset on preparation of the phosphorylated counterparts of protein for studying antifungal activities against susceptible dose-dependent to antimycotics.

作者信息

Qiao Yuanbiao, Song Li, Zhu Chenchen, Wang Qian, Guo Tianyan, Yan Yanhua, Li Qingshan

机构信息

Graduate Institute of Pharmaceutical Chemistry, Luliang University, Shanxi, PR China.

出版信息

Data Brief. 2017 Sep 23;15:370-375. doi: 10.1016/j.dib.2017.09.041. eCollection 2017 Dec.

Abstract

The data presented here are related to a research article entitled "Development of a phosphorylated protein system for inhibiting susceptible dose-dependent to available antimycotics: An allosteric regulation of protein" (Qiao et al., 2017) [1]. The data set includes three portions: (1) a relationship between reaction velocities of protein phosphorylation as a function of the substrate concentrations, determined in enzymatic reactions in aid of protein kinases; (2) a result of antifungal susceptibility testing of after it is selected in antimycotics; and (3) a comparison of protein expression in the susceptible dose-dependent fungus relative to the wild . In the first portion, the relationship of reaction velocities and substrate concentrations is expressed as an output from the inverse variation model. All data and analyses are made publicly available and citied in the research article using a style for

摘要

此处呈现的数据与一篇名为《开发一种对可用抗真菌药物敏感剂量依赖性抑制的磷酸化蛋白系统:蛋白的变构调节》(乔等人,2017年)[1]的研究文章相关。数据集包括三个部分:(1)在蛋白激酶辅助的酶促反应中测定的蛋白磷酸化反应速度与底物浓度的函数关系;(2)在抗真菌药物中筛选后进行的抗真菌药敏试验结果;(3)敏感剂量依赖性真菌与野生型相比的蛋白表达比较。在第一部分中,反应速度与底物浓度的关系表示为反变模型的输出。所有数据和分析均已公开提供,并在研究文章中按照一种风格引用

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