Toro-Ramos Tatiana, Lee Dong-Hwa, Kim Youngin, Michaelides Andreas, Oh Tae Jung, Kim Kyoung Min, Jang Hak Chul, Lim Soo
1 Noom, Inc. , New York, New York.
2 Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital , Seongnam, South Korea .
Metab Syndr Relat Disord. 2017 Nov;15(9):465-473. doi: 10.1089/met.2017.0062. Epub 2017 Oct 16.
There are inconsistent results for the effectiveness of using smartphone applications (apps) or websites on weight loss. We investigated the efficacy of a smartphone intervention using a designated app that utilizes a lifestyle intervention-focused approach, including a human coaching element, toward weight loss in overweight or obese Korean adults.
One hundred four adults aged 20-60 years with a body mass index ≥23 kg/m, who signed up for a smartphone program for weight loss (using the Noom app), were recruited. Participants received an in-person orientation about the study and app use, and a baseline blood sample was obtained. The in-app intervention with daily behavior and nutrition education content and coaching lasted 15 weeks. The primary endpoint of the study was a change in weight. The secondary endpoints were changes in metabolic risk factors such as blood pressure, waist circumference, and glucose and lipid profiles. Body composition changes were also assessed, and body weight at 52 weeks was measured to ascertain long-term effects.
Participants showed a clinically significant weight loss effect of -7.5% at the end of the 15-week program (P < 0.001), and at a 52-week follow-up, a weight loss effect of -5.2% was maintained. At 15 weeks, percent body fat and visceral fat decreased by -6.0 ± 5.4% and -3.4 ± 2.7 kg, respectively (both P < 0.001). Fasting glucose level also decreased significantly by -5.7 ± 14.6 mg/dL at 15 weeks. Lipid parameters showed significant improvements, except for high-density lipoprotein cholesterol. The frequency of logging meals and exercise was associated with body fat loss.
This advanced smartphone app was a useful tool to maintain weight loss in overweight or obese people.
关于使用智能手机应用程序（应用）或网站进行减肥的有效性，研究结果并不一致。我们调查了一款指定应用程序的智能手机干预措施对韩国超重或肥胖成年人减肥的效果，该应用采用以生活方式干预为重点的方法，包括人工指导元素。
招募了104名年龄在20 - 60岁、体重指数≥23kg/m²且报名参加智能手机减肥计划（使用Noom应用）的成年人。参与者接受了关于该研究和应用使用的现场指导，并采集了基线血样。应用内包含日常行为和营养教育内容以及指导的干预持续了15周。该研究的主要终点是体重变化。次要终点是代谢风险因素的变化，如血压、腰围以及血糖和血脂谱。还评估了身体成分的变化，并测量了52周时的体重以确定长期效果。
在15周计划结束时，参与者显示出临床上显著的体重减轻效果，减重7.5%（P < 0.001），在52周的随访中，体重减轻效果维持在5.2%。在15周时，体脂百分比和内脏脂肪分别下降了6.0±5.4%和3.4±2.7kg（均P < 0.001）。空腹血糖水平在15周时也显著下降了5.7±14.6mg/dL。除高密度脂蛋白胆固醇外，血脂参数有显著改善。记录饮食和运动的频率与体脂减少有关。
这款先进的智能手机应用是超重或肥胖人群维持体重减轻的有用工具。
