The Benson-Henry Institute for Mind Body Medicine at Massachusetts General Hospital, 151 Merrimac Street, 4th Floor, Boston, MA 02143, United States.
Complement Ther Med. 2013 Aug;21(4):286-93. doi: 10.1016/j.ctim.2013.05.005. Epub 2013 Jun 15.
This pilot study evaluated the effectiveness of a comprehensive mind body intervention for weight loss in overweight and obesity and the maintenance of weight loss at 6-month follow-up.
Thirty-one overweight and obese employees (Body Mass Index (BMI) 28.6-47.9 kg/m²) from a large corporation participated in a 20-week comprehensive mind body intervention targeting weight loss.
Weight, BMI, waist and hip circumference, rate pressure product (RPP), blood pressure, fasting blood glucose, cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and psychological variables were collected at baseline, post-intervention, and 6-month follow-up.
Using linear mixed model analyses, the intervention resulted in significant mean weight loss (-4.3 kg, 95% CI -5.8 to -2.8), decreases in BMI (-1.51, 95% CI -2.1 to -1.0), hip circumference measurement (-4.3 cm, 95% CI -6.9 to -1.5), and triglyceride levels (95% CI -33.1 to -4.8). In 6-month follow-up after intervention, statistically significant improvements in weight, BMI and waist measurement were sustained. Participants also showed positive changes in self-reported psychological indices: food-related disinhibition, and hunger both decreased significantly (p<0.01); general self-efficacy increased (p<0.05); positive affect increased (p<0.001); physical function and self-esteem increased (p<0.01); and measures of health-promoting behaviors on 4 subscales (health responsibility, physical activity, nutrition, and stress management) also showed statistically significant improvements (p<0.001) at post-intervention and 6-month follow-up.
This comprehensive mind body intervention showed modest effects on physical, laboratory, and psychological outcomes, both immediately following treatment and at 6-month follow-up, in overweight and obese individuals.
本初步研究评估了综合身心干预对超重和肥胖人群减肥的有效性，以及在 6 个月随访时保持减肥效果。
来自一家大公司的 31 名超重和肥胖员工（体重指数（BMI）28.6-47.9kg/m²）参加了一项为期 20 周的综合身心干预，以减肥为目标。
体重、BMI、腰围和臀围、心率血压乘积（RPP）、血压、空腹血糖、胆固醇、甘油三酯、高密度脂蛋白（HDL）、低密度脂蛋白（LDL）和心理变量在基线、干预后和 6 个月随访时进行收集。
使用线性混合模型分析，干预导致了显著的平均体重减轻（-4.3kg，95%置信区间-5.8 至-2.8）、BMI 降低（-1.51，95%置信区间-2.1 至-1.0）、臀围测量值降低（-4.3cm，95%置信区间-6.9 至-1.5）和甘油三酯水平降低（95%置信区间-33.1 至-4.8）。在干预后的 6 个月随访中，体重、BMI 和腰围测量值的改善仍具有统计学意义。参与者还报告了心理指标的积极变化：与食物相关的抑制和饥饿感均显著降低（p<0.01）；一般自我效能感增加（p<0.05）；积极情绪增加（p<0.001）；身体功能和自尊增加（p<0.01）；在 4 个亚量表上的健康促进行为测量（健康责任、身体活动、营养和压力管理）也显示出在干预后和 6 个月随访时具有统计学意义的改善（p<0.001）。
这种综合身心干预对超重和肥胖个体的身体、实验室和心理结果均显示出适度的效果，无论是在治疗后立即还是在 6 个月随访时。
