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与卒中后自杀死亡相关的因素。

Factors associated with post-stroke suicidal death.

机构信息

Department of Psychiatry, Sungkyunkwan University School of Medicine, Samsung Medical Center, South Korea.

Department of Research Planning, Mental Health Research Institute, National Center for Mental Health, South Korea.

出版信息

J Psychiatr Res. 2018 Jan;96:135-137. doi: 10.1016/j.jpsychires.2017.10.005. Epub 2017 Oct 7.

Abstract

BACKGROUND AND PURPOSE

The aim of this study was to estimate the relative risk of suicidal death compared to the general population and to identify risk factors for suicidal death among stroke patients.

METHODS

Our sample consisted of 7175 patients who were diagnosed with stroke and admitted at Asan Medical Center from January 2005 to December 2012. Information on suicidal death was obtained from the database of the Korean National Statistical Office. The standardized mortality ratio (SMR) for post-stroke suicide was estimated. Additionally, we conducted a 1:6 case-control study using patients who did not commit suicide.

RESULTS

Thirty patients committed suicidal death, with the mean time interval between hospital admission and suicide being 1.9 ± 1.8 years. The SMR for suicide was 2.14 (95% confidence interval [CI], 1.44-3.05). Case-control analysis revealed that diabetes mellitus, depression, and large ischemic lesions in the subcortex and brainstem were significantly associated with suicidal death.

CONCLUSIONS

The risk of suicidal death is approximately 2 times higher than that in the general population. Depression, diabetes, and large lesions in specific locations should be considered in the implementation of suicide prevention strategies in stroke patients.

摘要

背景与目的

本研究旨在评估与普通人群相比,卒中患者自杀死亡的相对风险,并确定卒中患者自杀死亡的危险因素。

方法

我们的样本包括 7175 名 2005 年 1 月至 2012 年 12 月期间在 Asan 医疗中心被诊断为卒中并入院的患者。自杀死亡的信息来自韩国国家统计局数据库。估计了卒中后自杀的标准化死亡率(SMR)。此外,我们使用未自杀的患者进行了 1:6 的病例对照研究。

结果

30 名患者自杀死亡,从住院到自杀的平均时间间隔为 1.9±1.8 年。自杀的 SMR 为 2.14(95%置信区间[CI],1.44-3.05)。病例对照分析显示,糖尿病、抑郁和皮质下及脑干大缺血性病变与自杀死亡显著相关。

结论

自杀死亡的风险大约是普通人群的 2 倍。在实施卒中患者的自杀预防策略时,应考虑抑郁、糖尿病和特定部位的大病变。

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