Neugebauer D, Weber G
Hautklinik am Klinikum Nürnberg.
Z Hautkr. 1988 Jul 15;63(7):585-6, 589-90.
In 59 patients suffering from chronic psoriasis, we tested the therapeutic effects of yohimbine and colchicine. It is well known that yohimbine, an alpha 2-adrenoceptor-blocking agent, reduces the secretion of insulin and the platelet factors. 85% of our psoriatic patients showed decreased values for somatostatin, in association with hyperinsulinemia (88%) and low platelet counts. Successful therapy with yohimbine resulted in the normalization of the pathological blood levels.
在59例慢性银屑病患者中,我们测试了育亨宾和秋水仙碱的治疗效果。众所周知,育亨宾作为一种α2-肾上腺素能受体阻滞剂,会减少胰岛素和血小板因子的分泌。我们85%的银屑病患者生长抑素水平降低,同时伴有高胰岛素血症(88%)和血小板计数低。育亨宾治疗成功使异常的血液水平恢复正常。