与精神分裂症相比，躁狂症中抗精神病药物所致肌张力障碍的发生率更高。
Higher frequency of neuroleptic-induced dystonia in mania than in schizophrenia.
作者信息
Nasrallah H A, Churchill C M, Hamdan-Allan G A
机构信息
Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210.
出版信息
Am J Psychiatry. 1988 Nov;145(11):1455-6. doi: 10.1176/ajp.145.11.1455.
PMID:2903686
Abstract
In a study of 135 schizophrenic and 46 manic male patients treated with neuroleptics, a significantly higher proportion of the manic patients (26.1%) than of the schizophrenic patients (5.9%) developed acute dystonia. This suggests a higher vulnerability to acute extrapyramidal symptoms in mania.
摘要
在一项对135名接受抗精神病药物治疗的精神分裂症男性患者和46名躁狂症男性患者的研究中，躁狂症患者（26.1%）发生急性肌张力障碍的比例显著高于精神分裂症患者（5.9%）。这表明躁狂症患者对急性锥体外系症状的易感性更高。
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