Sieber David A, Adams William P
Private practice in San Francisco, CA.
Department of Plastic Surgery, University of Texas Southwestern, Dallas, TX.
Aesthet Surg J. 2017 Sep 1;37(8):887-891. doi: 10.1093/asj/sjx127.
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) continues to be a rare and elusive malignancy. Because BIA-ALCL does not behave like traditional lymphomas, additional research needs to be conducted to further delineate the lymphoproliferative nature of BIA-ALCL. An estimated 35 million women worldwide have breast implants and the total reported deaths from BIA-ALCL is 12 to date. The term micromort was introduced in 1979 by Ronald Howard as a person's risk of dying as 1 in a million. Drinking 0.5 L of wine or walking 17 miles all increase your risk of death by 1 micromort. Risk of death from BIA-ALCL is 0.4 micromorts for a woman having bilateral breast implants. This information is important for counseling new patients and those presenting with delayed onset seromas.
乳房植入物相关间变性大细胞淋巴瘤（BIA-ALCL）仍然是一种罕见且难以捉摸的恶性肿瘤。由于BIA-ALCL的行为不像传统淋巴瘤，因此需要进行更多研究以进一步阐明BIA-ALCL的淋巴增殖性质。全球估计有3500万女性植入了乳房植入物，迄今为止，BIA-ALCL报告的死亡总数为12例。“微死亡”一词于1979年由罗纳德·霍华德提出，指一个人死亡风险为百万分之一。饮用0.5升葡萄酒或步行17英里都会使死亡风险增加1微死亡。对于双侧植入乳房植入物的女性，死于BIA-ALCL的风险为0.4微死亡。这些信息对于为新患者以及出现延迟性血清肿的患者提供咨询非常重要。
