Noothong Sitchuphong, Inthasorn Perapong, Warnnissorn Malee
Department of Obstetrics and Gynaecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok 10700, Thailand.
Department of Obstetrics and Gynaecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok 10700, Thailand.
Taiwan J Obstet Gynecol. 2017 Oct;56(5):628-631. doi: 10.1016/j.tjog.2017.08.009.
To determine the prevalence of patients with CIN1 or less from LEEP specimens in patients with colposcopic biopsy proven CIN2 or 3.
This study was a retrospective-descriptive chart review. Clinical data were retrieved from medical records of women with CIN2 or 3 from colposcopic biopsy who subsequently underwent LEEP procedure between 2004 and 2014. All pathological slides were reviewed by the gynecologic pathologist. Statistical analyses were performed.
Of 210 patients, 14 patients were excluded from the study. 196 patients were in eligible criteria and data were analyzed. There were 32 patients (16.3%) with CIN1 or less from LEEP specimens who previously had colposcopic biopsies proven CIN2 or 3. Only CIN2 from biopsy was the statistically significant risk factor of CIN1 or less in LEEP specimens. Odds ratio was 10.45 (95% confidence interval: 3.28-33.33, P < 0.001).
The prevalence of patients with CIN1 or less from LEEP specimens who previously had colposcopic biopsies proven CIN2 or 3 was 16.3%. CIN2 from biopsy was the statistically significant risk factor of CIN1 or less in LEEP specimens.
确定在经阴道镜活检证实为CIN2或3的患者中，leep标本中CIN1及以下病变患者的患病率。
本研究为回顾性描述性图表回顾。从2004年至2014年间接受leep手术的经阴道镜活检证实为CIN2或3的女性患者的病历中检索临床数据。所有病理切片均由妇科病理学家复查。进行了统计分析。
210例患者中，14例被排除在研究之外。196例患者符合纳入标准并对数据进行分析。在之前经阴道镜活检证实为CIN2或3的患者中，有32例（16.3%）leep标本为CIN1及以下病变。活检仅为CIN2是leep标本中CIN1及以下病变的统计学显著危险因素。比值比为10.45（95%置信区间：3.28 - 33.33，P < 0.001）。
之前经阴道镜活检证实为CIN2或3的患者中，leep标本为CIN1及以下病变的患病率为16.3%。活检为CIN2是leep标本中CIN1及以下病变的统计学显著危险因素。
