Sakka Samir G
Department of Anesthesiology and Operative Intensive Care Medicine, Medical Center Cologne-Merheim, University Witten/ Herdecke, Ostmerheimerstrasse 200, 51109, Cologne, Germany.
J Clin Monit Comput. 2018 Oct;32(5):787-796. doi: 10.1007/s10877-017-0073-4. Epub 2017 Oct 16.
Indocyanine green (ICG) is a water-soluble dye that is bound to plasma proteins when administered intravenously and nearly completely eliminated from the blood by the liver. ICG elimination depends on hepatic blood flow, hepatocellular function and biliary excretion. ICG elimination is considered as a useful dynamic test describing liver function and perfusion in the perioperative setting, i.e., in liver surgery and transplantation, as well as in critically ill patients. ICG plasma disappearance rate (ICG-PDR) which can be measured today by transcutaneous systems at the bedside is a valuable method for dynamic assessment of liver function and perfusion, and is regarded as a valuable prognostic tool in predicting survival of critically ill patients, presenting with sepsis, ARDS or acute liver failure.
吲哚菁绿（ICG）是一种水溶性染料，静脉注射后与血浆蛋白结合，并几乎完全由肝脏从血液中清除。ICG的清除取决于肝血流量、肝细胞功能和胆汁排泄。在围手术期，即肝手术和肝移植以及危重症患者中，ICG清除被认为是一种描述肝功能和灌注的有用动态测试。如今可通过床边经皮系统测量的ICG血浆消失率（ICG-PDR）是动态评估肝功能和灌注的一种有价值的方法，并且被视为预测患有脓毒症、急性呼吸窘迫综合征（ARDS）或急性肝衰竭的危重症患者生存情况的一种有价值的预后工具。
