Nesheim Steven R, Linley Laurie, Gray Kristen M, Zhang Tianchi, Shi Jing, Lampe Margaret A, FitzHarris Lauren F
Epidemiology Branch, Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, Sexually Transmitted Diseases and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
HIV Incidence and Case Surveillance Branch, Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, Sexually Transmitted Diseases and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
J Acquir Immune Defic Syndr. 2018 Jan 1;77(1):23-30. doi: 10.1097/QAI.0000000000001572.
Diagnoses of HIV infection among children in the United States have been declining; however, a notable percentage of diagnoses are among those born outside the United States. The impact of foreign birth among children with diagnosed infections has not been examined in the United States.
Using the Centers for Disease Control and Prevention National HIV Surveillance System, we analyzed data for children aged <13 years with diagnosed HIV infection ("children") in the United States (reported from 50 states and the District of Columbia) during 2008-2014, by place of birth and selected characteristics.
There were 1516 children [726 US born (47.9%) and 676 foreign born (44.6%)]. US-born children accounted for 70.0% in 2008, declining to 32.3% in 2013, and 40.9% in 2014. Foreign-born children have exceeded US-born children in number since 2011. Age at diagnosis was younger for US-born than foreign-born children (0-18 months: 72.6% vs. 9.8%; 5-12 years: 16.9% vs. 60.3%). HIV diagnoses in mothers of US-born children were made more often before pregnancy (49.7% vs. 21.4%), or during pregnancy (16.6% vs. 13.9%), and less often after birth (23.7% vs. 41%). Custodians of US-born children were more often biological parents (71.9% vs. 43.2%) and less likely to be foster or nonrelated adoptive parents (10.4% vs. 55.1%). Of 676 foreign-born children with known place of birth, 65.5% were born in sub-Saharan Africa and 14.3% in Eastern Europe. The top countries of birth were Ethiopia, Ukraine, Uganda, Haiti, and Russia.
The increasing number of foreign-born children with diagnosed HIV infection in the United States requires specific considerations for care and treatment.
美国儿童中艾滋病毒感染的诊断数量一直在下降;然而,相当大比例的诊断病例发生在出生于美国境外的儿童中。在美国,外国出生对确诊感染儿童的影响尚未得到研究。
利用疾病控制和预防中心的国家艾滋病毒监测系统,我们分析了2008 - 2014年期间美国(来自50个州和哥伦比亚特区报告)年龄小于13岁的确诊艾滋病毒感染儿童(“儿童”)的数据,按出生地和选定特征进行分析。
共有1516名儿童[726名在美国出生(47.9%)和676名外国出生(44.6%)]。美国出生的儿童在2008年占70.0%,到2013年降至32.3%,2014年为40.9%。自2011年以来,外国出生的儿童数量超过了美国出生的儿童。美国出生儿童的诊断年龄比外国出生儿童小(0 - 18个月:72.6%对9.8%;5 - 12岁:16.9%对60.3%)。美国出生儿童的母亲艾滋病毒诊断更多在怀孕前(49.7%对21.4%)或怀孕期间(16.6%对13.9%)做出,而在出生后做出的较少(23.7%对41%)。美国出生儿童的监护人更多是亲生父母(71.