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世界卫生组织对新出现的人类免疫缺陷病毒耐药性的应对措施及全球行动呼吁。

The World Health Organization's Response to Emerging Human Immunodeficiency Virus Drug Resistance and a Call for Global Action.

作者信息

Bertagnolio Silvia, Beanland Rachel L, Jordan Michael R, Doherty Meg, Hirnschall Gottfried

机构信息

HIV Department, World Health Organization.

Independent Public Health Specialist, Switzerland.

出版信息

J Infect Dis. 2017 Dec 1;216(suppl_9):S801-S804. doi: 10.1093/infdis/jix402.

DOI:10.1093/infdis/jix402
PMID:29040686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5853942/
Abstract

The global community, including the World Health Organization (WHO), has committed to ending the AIDS epidemic and to ensuring that 90% of people living with human immunodeficiency virus (HIV) are diagnosed, 90% start treatment, and 90% achieve and maintain virological suppression. The emergence of HIV drug resistance (HIVDR) as antiretroviral treatment programs expand could preclude the 90-90-90 targets adopted by the United Nations General Assembly at the High-Level Meeting on Ending AIDS from being achieved. The Global Action Plan on HIVDR is a call for collective action grounded on normative guidance providing a standardized and robust approach to monitoring, preventing, and responding to HIVDR over the next 5 years (2017-2021). WHO is committed to supporting country, global, regional, and national partners to implement and monitor the progress of the Global Action Plan. This article outlines the key components of WHO's strategy to tackle HIVDR and the role the organization takes in leading the global response to HIVDR.

摘要

包括世界卫生组织(WHO)在内的全球社会已致力于终结艾滋病流行,并确保90%的人类免疫缺陷病毒(HIV)感染者得到诊断,90%开始治疗,以及90%实现并维持病毒学抑制。随着抗逆转录病毒治疗项目的扩大,HIV耐药性(HIVDR)的出现可能会妨碍联合国大会在终结艾滋病问题高级别会议上通过的90-90-90目标的实现。《HIV耐药性全球行动计划》呼吁采取集体行动,其基于规范性指导方针,为未来5年(2017 - 2021年)监测、预防和应对HIVDR提供标准化且有力的方法。WHO致力于支持国家、全球、区域和国家级合作伙伴实施并监测《全球行动计划》的进展。本文概述了WHO应对HIVDR战略的关键组成部分以及该组织在引领全球应对HIVDR方面所发挥的作用。

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