Life Span Institute, University of Kansas, United States; Department of Psychology, University of South Carolina, United States; Department of Psychology, University of South Carolina, United States.
Speech-Language-Hearing, Sciences & Disorders, University of Kansas, United States.
Res Dev Disabil. 2017 Dec;71:169-180. doi: 10.1016/j.ridd.2017.10.004. Epub 2017 Oct 15.
Little research in fragile X syndrome (FXS) has prospectively examined early social communication.
To compare early social communication in infants with FXS, infant siblings of children with autism spectrum disorder (ASIBs), and typically developing (TD) infants.
Participants were 18 infants with FXS, 21 ASIBs, and 22 TD infants between 7.5-14.5 months. Social communication was coded using the Communication Complexity Scale during the administration of Autism Observation Scale for Infants.
Descriptively different patterns were seen across the three groups. Overall infants with FXS had lower social communication than ASIBs or TD infants when controlling for nonverbal cognitive abilities. However, infants with FXS had similar levels of social communication as ASIBs or TD infants during peek-a-boo. No differences were observed between ASIBs and TD infants. For all infants, higher social communication was related to lower ASD risk.
Findings provide insight into the developmental course of social communication in FXS. The dynamic nature of social games may help to stimulate communication in infants with FXS. Language interventions with a strong social component may be particularly effective for promoting language development in FXS.
脆性 X 综合征 (FXS) 的研究很少前瞻性地检查早期社交沟通。
比较 FXS 婴儿、自闭症谱系障碍婴儿兄弟姐妹 (ASIBs) 和典型发育 (TD) 婴儿的早期社交沟通。
参与者为 18 名 FXS 婴儿、21 名 ASIB 婴儿和 22 名 TD 婴儿，年龄在 7.5-14.5 个月之间。使用自闭症婴儿观察量表 (Autism Observation Scale for Infants) 进行测试时，使用沟通复杂性量表对社交沟通进行编码。
三个组的描述性模式存在差异。总体而言，控制非言语认知能力后，FXS 婴儿的社交沟通能力低于 ASIBs 或 TD 婴儿。然而，在玩躲猫猫游戏时，FXS 婴儿的社交沟通能力与 ASIBs 或 TD 婴儿相似。ASIBs 和 TD 婴儿之间没有差异。对于所有婴儿，较高的社交沟通能力与较低的自闭症风险相关。
研究结果深入了解了 FXS 中社交沟通的发展过程。社交游戏的动态性质可能有助于刺激 FXS 婴儿的沟通。具有强烈社交成分的语言干预措施可能对促进 FXS 中语言发展特别有效。
