McWilliams B J, Matthews H P
Cleft Palate J. 1979 Oct;16(4):363-72.
Intelligence and social development were evaluated in 226 subjects with palatal clefts. The subjects were divided into four groups composed of 111 with unilateral complete clefts of the lip and palate (Unilateral Group); 16 with unilateral complete clefts with associated congenital malformations (Unilateral-C Group); 76 with clefts of the palate only (Palatal Group; and 39 with clefts of the palate only with other congenital malformations (Palatal-C Group). Comparisons among groups suggested that subjects in the Unilateral Group were most competent both mentally and socially followed by those in the Palatal, Unilateral-C, and Palatal-C Groups. The presence of congenital abnormalities other than cleft increased the risk of developmental disabilities, particularly in subjects with isolated palatal clefts.
对226名腭裂患者的智力和社交发展进行了评估。这些受试者被分为四组：111名单侧唇腭裂患者（单侧组）；16名单侧完全性唇腭裂合并相关先天性畸形患者（单侧-C组）；76名单纯腭裂患者（腭裂组）；39名单纯腭裂合并其他先天性畸形患者（腭裂-C组）。组间比较表明，单侧组的受试者在智力和社交方面最有能力，其次是腭裂组、单侧-C组和腭裂-C组。除腭裂外的先天性异常增加了发育障碍的风险，尤其是在单纯腭裂患者中。
