Jiao Xiao, Zou Jianyin, Liu Suru, Guan Jian, Yi Hongliang, Yin Shankai
Otolaryngology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai, China.
Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, China.
PeerJ. 2017 Oct 13;5:e3918. doi: 10.7717/peerj.3918. eCollection 2017.
The objective of this study was to explore the differences in upper airway morphology between positional (POSA) and non-positional (NPOSA) obstructive sleep apnea.
This retrospective study enrolled 75 patients (45 NPOSA and 30 POSA) who underwent polysomnography (PSG) and computed tomography (CT). The differences in, and relationships of, the PSG values and CT data between POSA and NPOSA were analyzed.
Significant ( < 0.05) differences between the two groups were found in the apnea/hypopnea index (AHI), lateral-AHI (L-AHI), soft palate length (SPL), cross-sectional palatopharyngeal area, and the coronal diameter (CD) of the palatopharyngeal area at the narrowest part of the glossopharynx, which were all higher in POSA, except for SPL, AHI, and L-AHI. L-AHI was correlated with the cross-sectional area ( = - 0.306, = 0.008) and CD ( = - 0.398, < 0.001) of the palatopharyngeal area, the cross-sectional area ( = - 0.241, = 0.038) and CD ( = - 0.297, = 0.010) of the narrowest level of the glossopharynx, the CD of the glossopharynx ( = 0.284, = 0.013), body mass index (BMI, = 0.273, = 0.018), SPL ( = 0.284, = 0.014), and vallecula-tip of tongue ( = 0.250, = 0.030). The SPL and CD at the narrowest part of the glossopharynx were included in the simplified screening model.
In NPOSA, the CD of the upper airway was smaller, and the soft palate was longer, than in POSA. These differences may play significant roles in explaining the main differences between NPOSA and POSA.
本研究旨在探讨体位性阻塞性睡眠呼吸暂停（POSA）与非体位性阻塞性睡眠呼吸暂停（NPOSA）在上气道形态上的差异。
本回顾性研究纳入了75例接受多导睡眠监测（PSG）和计算机断层扫描（CT）的患者（45例NPOSA和30例POSA）。分析了POSA和NPOSA之间PSG值和CT数据的差异及相关性。
两组之间在呼吸暂停/低通气指数（AHI）、侧方AHI（L-AHI）、软腭长度（SPL）、腭咽横截面积以及舌咽最窄处腭咽区域的冠状径（CD）方面存在显著差异（P<0.05），除SPL、AHI和L-AHI外，这些指标在POSA组中均更高。L-AHI与腭咽区域的横截面积（r=-0.306，P=0.008）和CD（r=-0.398，P<0.001）、舌咽最窄水平处的横截面积（r=-0.241，P=0.038）和CD（r=-0.297，P=0.010）、舌咽的CD（r=0.284，P=0.013）、体重指数（BMI，r=0.273，P=0.018）、SPL（r=0.284，P=0.014）以及会厌-舌尖距离（r=0.250，P=0.030）相关。舌咽最窄处的SPL和CD被纳入简化筛查模型。
与POSA相比，NPOSA的上气道CD较小，软腭较长。这些差异可能在解释NPOSA和POSA之间的主要差异方面发挥重要作用。
