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体位疗法在成人阻塞性睡眠呼吸暂停中的应用。

Usage of positional therapy in adults with obstructive sleep apnea.

作者信息

de Vries Grietje E, Hoekema Aarnoud, Doff Michiel H J, Kerstjens Huib A M, Meijer Petra M, van der Hoeven Johannes H, Wijkstra Peter J

机构信息

University of Groningen, University Medical Center Groningen, Department of Pulmonary Medicine and Tuberculosis, Groningen, the Netherlands: University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, the Netherlands.

University of Groningen, University Medical Center Groningen, Department of Oral and Maxillofacial Surgery, Groningen, the Netherlands.

出版信息

J Clin Sleep Med. 2015 Jan 15;11(2):131-7. doi: 10.5664/jcsm.4458.

Abstract

STUDY OBJECTIVES

Many positional therapy (PT) strategies are available for treating positional obstructive sleep apnea (OSA). PT is primarily supplied to selected patients as a secondary treatment option when other therapies have failed. To our knowledge this is the largest study to date to assess effectiveness and long-term compliance of PT (both commercial waistband and self-made constructions, mimicking the tennis ball technique) as primary treatment in patients with different positional OSA severities.

METHODS

PT was used by 53 patients, of which 40 patients underwent a follow-up polygraphic evaluation under treatment after a median time interval of 12 weeks. Patients were routinely contacted regarding their clinical status and treatment compliance.

RESULTS

PT was successful in 27 out of 40 patients (68%). Overall AHI reduced significantly from a median (interquartile range [IQR]) AHI of 14.5 (10.7-19.6) to 5.9 (3.1-8.5), p < 0.001. The commercial waistband and self-made constructions were equally effective (median (IQR) reduction in overall AHI (Δ9.6 (5.5-11.9) and Δ6.8 (3.2-11.3) respectively), p = 0.22). Short-term compliance was good as most patients used PT more than 7 hours/night (mean 7.2 ± SD 1.4) and more than 6 days/ week (mean 6.5 ± SD 1.3). However, after mean 13±5 months, 26 patients (65%) reported they no longer used PT, especially patients with moderate positional OSA (89%).

CONCLUSIONS

On the short-term, PT using the tennis ball technique, is an easy method to treat most patients with positional OSA, showing significant reductions in AHI. Unfortunately, long-term compliance is low and close follow-up of patients on PT with regard to their compliance is necessary.

摘要

研究目的

有多种体位疗法(PT)策略可用于治疗体位性阻塞性睡眠呼吸暂停(OSA)。当其他治疗方法失败时,PT主要作为二线治疗方案提供给特定患者。据我们所知,这是迄今为止规模最大的一项研究,旨在评估PT(包括商业腰带和自制装置,模仿网球技术)作为不同体位性OSA严重程度患者的一线治疗方法的有效性和长期依从性。

方法

53例患者使用了PT,其中40例患者在中位时间间隔12周后接受了治疗期间的多导睡眠图随访评估。定期联系患者了解其临床状况和治疗依从性。

结果

40例患者中有27例(68%)使用PT成功。总体呼吸暂停低通气指数(AHI)从中位值(四分位间距[IQR])14.5(10.7 - 19.6)显著降至5.9(3.1 - 8.5),p < 0.001。商业腰带和自制装置同样有效(总体AHI的中位值(IQR)降低分别为Δ9.6(5.5 - 11.9)和Δ6.8(3.2 - 11.3)),p = 0.22)。短期依从性良好,因为大多数患者每晚使用PT超过7小时(平均7.2 ±标准差1.4),每周使用超过6天(平均6.5 ±标准差1.3)。然而,平均13 ± 5个月后,26例患者(65%)报告不再使用PT,尤其是中度体位性OSA患者(89%)。

结论

短期内,采用网球技术的PT是治疗大多数体位性OSA患者的简便方法,AHI显著降低。不幸的是,长期依从性较低,因此有必要密切随访接受PT治疗患者的依从性情况。

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