生命科学的先进荧光显微镜技术。

Danial John S H, Aguib Yasmine, Yacoub Magdi H

Department of Chemistry, University of Oxford, Oxford OX1 3TA, United Kingdom.

Present address: Max Planck Institute for Intelligent systems, Heisenbergstraße 3, 70569 Stuttgart, Germany.

Glob Cardiol Sci Pract. 2016 Jun 30;2016(2):e201616. doi: 10.21542/gcsp.2016.16.

The development of super-resolved fluorescence microscopy, for which the Nobel Prize was awarded in 2014, has been a topic of interest to physicists and biologists alike. It is inevitable that numerous questions in biomedical research cannot be answered by means other than direct observation. In this review, advances to fluorescence microscopy are covered in a widely accessible fashion to facilitate its use in decisions related to its acquisition and utilization in biomedical research.

2014年诺贝尔物理学奖授予了超分辨荧光显微镜技术，这一技术的发展一直是物理学家和生物学家共同关注的话题。生物医学研究中的众多问题不可避免地只能通过直接观察来解答。在本综述中，我们以通俗易懂的方式介绍了荧光显微镜技术的进展，以方便其在生物医学研究中购置和使用决策方面的应用。