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通过C-H键官能化形成双C-S键：由N-取代芳胺和元素硫合成苯并噻唑和萘并[2,1-d]噻唑

Double C-S bond formation via C-H bond functionalization: synthesis of benzothiazoles and naphtho[2,1-d]thiazoles from N-substituted arylamines and elemental sulfur.

作者信息

Zhu Xiaoming, Yang Yuzhong, Xiao Genhua, Song Jianxin, Liang Yun, Deng Guobo

机构信息

National & Local Joint Engineering Laboratory for New Petro-chemical Materials and Fine Utilization of Resources, Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education, Key Laboratory of the Assembly and Application of Organic Functional Molecules, Hunan Normal University, Changsha, Hunan 410081, China.

出版信息

Chem Commun (Camb). 2017 Oct 31;53(87):11917-11920. doi: 10.1039/c7cc07366f.

DOI:10.1039/c7cc07366f
PMID:29044251
Abstract

A novel, atom economic, and environmentally friendly method for the synthesis of 2-substituted benzothiazoles and 2-substituted naphtho[2,1-d]thiazoles from N-substituted arylamines and elemental sulfur has been developed under metal-free conditions. The reaction underwent the process of double C-S bond formation through C-H bond functionalization.

摘要

已开发出一种新颖、原子经济且环境友好的方法，可在无金属条件下由N-取代芳胺和元素硫合成2-取代苯并噻唑和2-取代萘并[2,1-d]噻唑。该反应通过C-H键官能化经历了双C-S键形成过程。

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