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低强度激光照射对人牙髓细胞增殖的影响:一篇叙述性综述。

The effects of low level laser irradiation on proliferation of human dental pulp: a narrative review.

作者信息

Staffoli S, Romeo U, Amorim R N S, Migliau G, Palaia G, Resende L, Polimeni A

机构信息

Sapienza University of Rome, Italy, Department of Oral and Maxillofacial Sciences.

Federal University of Juiz de Fora, Brazil.

出版信息

Clin Ter. 2017 Sep-Oct;168(5):e320-e326. doi: 10.7417/T.2017.2028.

Abstract

Mesenchymal stem cells (MSCs) have the capability for self-renewal, proliferation, and differentiation in various types of specialized cells, so they are very important in cellular therapies. MSC from dental pulp are simply obtainable and have high proliferative capability. Among the therapies that can stimulate the proliferation of certain cell types, low-level laser therapy (LLLT) stands out. The target of this study is to perform a literature review to investigate these effects of low-level laser irradiation on proliferation of human dental pulp.The electronic search of scientific papers was conducted in the Lilacs, Scielo, Medline and PubMed databases through scientific articles published in national and international journals in the past 20 years.The results of this review suggest that LLLT may be a useful and important tool for future advances in cell therapy and tissue engineering associated to stem cells. Studies on cell therapy for regenerating dental tissues has already been done, and shows promising results.

摘要

间充质干细胞(MSCs)具有自我更新、增殖以及分化为各种类型特化细胞的能力,因此它们在细胞治疗中非常重要。牙髓间充质干细胞易于获取且具有高增殖能力。在能够刺激某些细胞类型增殖的疗法中,低强度激光疗法(LLLT)脱颖而出。本研究的目的是进行一项文献综述,以探究低强度激光照射对人牙髓增殖的这些影响。通过检索过去20年在国内和国际期刊上发表的科学文章,在Lilacs、Scielo、Medline和PubMed数据库中对科学论文进行了电子检索。该综述结果表明,低强度激光疗法可能是未来与干细胞相关的细胞治疗和组织工程取得进展的一种有用且重要的工具。关于再生牙组织的细胞治疗研究已经开展,并显示出有前景的结果。

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