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蒙古家畜中绵羊γ-疱疹病毒2型的分子流行病学调查及基因特征分析

Molecular epidemiological survey and genetic characterization of ovine gammaherpesvirus-2 in Mongolian livestock.

作者信息

Ochirkhuu Nyamsuren, Konnai Satoru, Odbileg Raadan, Murata Shiro, Ohashi Kazuhiko

机构信息

Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.

Laboratory of Virology, Institute of Veterinary Medicine, Mongolia University of Life Science, Khan-Uul district, Zaisan 17042, Ulaanbaatar, Mongolia.

出版信息

J Vet Med Sci. 2017 Dec 22;79(12):2040-2042. doi: 10.1292/jvms.17-0203. Epub 2017 Oct 19.

Abstract

Sheep-associated malignant catarrhal fever (SA-MCF), caused by ovine gammaherpesvirus-2 (OvHV-2), is a fatal disease in all ruminants. The epidemiological survey and molecular characterization of OvHV-2 in Mongolian livestock were performed. Of 928 blood samples, 14 were positive for OvHV-2 in sheep and native cattle from Tsenkher County and in sheep from Lun County. Phylogenetic analyses revealed that the tegument gene of OvHV-2 sequences from Mongolian animals is identical to that in animals from Egypt, India, and Turkey, and is 98.0% similar to that in animals from Germany and Brazil. To our knowledge, this is the first confirmed report of OvHV-2 in Mongolian livestock, and could provide useful information for controlling SA-MCF.

摘要

绵羊相关的恶性卡他热(SA-MCF)由绵羊γ疱疹病毒2型(OvHV-2)引起,是所有反刍动物的一种致命疾病。对蒙古家畜中的OvHV-2进行了流行病学调查和分子特征分析。在928份血样中,来自森赫县的绵羊和本地牛以及伦县的绵羊中有14份OvHV-2呈阳性。系统发育分析表明,蒙古动物的OvHV-2序列的被膜基因与埃及、印度和土耳其动物的相同,与德国和巴西动物的相似性为98.0%。据我们所知,这是蒙古家畜中首次确诊的OvHV-2报告,可为控制SA-MCF提供有用信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/733b/5745187/47ff8218ac27/jvms-79-2040-g001.jpg

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