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在埃塞俄比亚一家转诊医院中,使用经过验证的工具TAI对哮喘患者吸入药物的不依从情况及相关因素进行研究。

Non adherence to inhalational medications and associated factors among patients with asthma in a referral hospital in Ethiopia, using validated tool TAI.

作者信息

Ayele Asnakew Achaw, Tegegn Henok Getachew

机构信息

Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, P.O.Box: 196, Gondar, Ethiopia.

出版信息

Asthma Res Pract. 2017 Oct 6;3:7. doi: 10.1186/s40733-017-0035-0. eCollection 2017.

Abstract

BACKGROUND

Asthma is a chronic inflammatory condition of the airways that affects roughly 358 million people globally. It is a serious global health problem with an increasing prevalence worldwide. Most people affected are in low- and middle-income countries including Ethiopia. The association between non -adherence and poor disease control is clearly stated in different literatures. The main objective of the present study was to assess self-reported non- adherence level and to identify the potential factors associated with non-adherence.

METHODS

An institution based cross-sectional study was conducted in university of Gondar teaching and referral hospital. The data was collected using a validated tool called Test of Adherence to Inhalers (TAI).

RESULT

Among the total of study participants, higher proportions of patients were female (57.3%). Large number of the respondents (59.1%) were Unable to read and write. 18.3% of inhalational user asthmatic patients were not adherent to inhalational medications. According to this study only 49.4% of the respondents were adherent to inhalations and 32.3% of them were intermediate adherent to inhalational anti asthmatics medications. Lack of education about the Proper use of inhalational anti-asthmatics medications, poly pharmacy and co-morbidities were statistically significant factors associated with non-adherence.

CONCLUSION

The rate of non-adherence to inhalational anti asthmatics is high. Therefore, promoting optimal medication adherences through education, proper patient consultation is essential to optimize the benefits of treatment. Measurement of the degree of non-adherence to inhaled treatment in each individual patient is important in early interventional practice.

摘要

背景

哮喘是一种气道慢性炎症性疾病,全球约有3.58亿人受其影响。它是一个严重的全球健康问题,在世界范围内患病率不断上升。大多数受影响的人来自包括埃塞俄比亚在内的低收入和中等收入国家。不同文献中都明确指出了不依从与疾病控制不佳之间的关联。本研究的主要目的是评估自我报告的不依从水平,并确定与不依从相关的潜在因素。

方法

在贡德尔大学教学与转诊医院进行了一项基于机构的横断面研究。数据通过一种名为吸入器依从性测试(TAI)的经过验证的工具收集。

结果

在所有研究参与者中,女性患者比例较高(57.3%)。大量受访者(59.1%)不识字。18.3%的吸入器使用者哮喘患者不坚持使用吸入药物。根据这项研究,只有49.4%的受访者坚持吸入治疗,其中32.3%为中度坚持使用吸入性抗哮喘药物。对正确使用吸入性抗哮喘药物缺乏教育、多种药物治疗和合并症是与不依从相关的具有统计学意义的因素。

结论

吸入性抗哮喘药物的不依从率很高。因此,通过教育促进最佳药物依从性,进行适当的患者咨询对于优化治疗效果至关重要。在早期干预实践中,测量每个患者吸入治疗的不依从程度很重要。

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