平行测序的生命，或者是什么让大型测序项目取得成功。

Parallel sequencing lives, or what makes large sequencing projects successful.

机构信息

Gene Regulation, Stem Cells and Cancer Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Dr. Aiguader 88, 08003 Barcelona, Spain.

Universitat Pompeu Fabra (UPF), Barcelona, Spain.

出版信息

Gigascience. 2017 Nov 1;6(11):1-6. doi: 10.1093/gigascience/gix100.

DOI:10.1093/gigascience/gix100

PMID:29048533

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5714127/

Abstract

T47D_rep2 and b1913e6c1_51720e9cf were 2 Hi-C samples. They were born and processed at the same time, yet their fates were very different. The life of b1913e6c1_51720e9cf was simple and fruitful, while that of T47D_rep2 was full of accidents and sorrow. At the heart of these differences lies the fact that b1913e6c1_51720e9cf was born under a lab culture of Documentation, Automation, Traceability, and Autonomy and compliance with the FAIR Principles. Their lives are a lesson for those who wish to embark on the journey of managing high-throughput sequencing data.

摘要

T47D_rep2 和 b1913e6c1_51720e9cf 是两个 Hi-C 样本。它们在同一时间产生并处理，但命运却截然不同。b1913e6c1_51720e9cf 的生活简单而充实，而 T47D_rep2 的生活则充满了意外和悲伤。这些差异的核心在于 b1913e6c1_51720e9cf 是在文档、自动化、可追溯性和自主性的实验室文化以及符合 FAIR 原则的条件下诞生的。它们的生活为那些希望开始管理高通量测序数据之旅的人提供了一个教训。