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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Drnková J, Nováková O, Pelouch V, Ostádal B, Kubista V

Department of Animal Physiology and Developmental Biology, Faculty of Natural Sciences, Charles University, Vinicná, Czechoslovakia.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1988;90(1):257-61. doi: 10.1016/0742-8413(88)90130-2.

After a single injection of 40 mg kg-1 of isoprenaline to the carp, lysophospholipids appear in the tissue of the heart ventricle, ethanolamine plasmalogens increase and choline plasmalogens decrease; phosphatidylinositol is lowered in the spongious layer only. 2. Daily administration of 5 mg kg-1 of the drug leads, after 5 doses, to a dramatic decrease of the diphosphatidylglycerol content; during the subsequent 5 and 10 doses a return to normal values occurs. Shifts in plasmalogens are similar to those found after a single high dose. Some other phospholipids change significantly. 3. All changes reveal that the spongious musculature is more sensitive to the drug than the compact one.

Drnková J, Nováková O, Pelouch V, Ostádal B, Kubista V

Department of Animal Physiology and Developmental Biology, Faculty of Natural Sciences, Charles University, Vinicná, Czechoslovakia.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1988;90(1):257-61. doi: 10.1016/0742-8413(88)90130-2.

After a single injection of 40 mg kg-1 of isoprenaline to the carp, lysophospholipids appear in the tissue of the heart ventricle, ethanolamine plasmalogens increase and choline plasmalogens decrease; phosphatidylinositol is lowered in the spongious layer only. 2. Daily administration of 5 mg kg-1 of the drug leads, after 5 doses, to a dramatic decrease of the diphosphatidylglycerol content; during the subsequent 5 and 10 doses a return to normal values occurs. Shifts in plasmalogens are similar to those found after a single high dose. Some other phospholipids change significantly. 3. All changes reveal that the spongious musculature is more sensitive to the drug than the compact one.