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与本科生合作,为生物化学社区资源做贡献。

Collaborating with Undergraduates To Contribute to Biochemistry Community Resources.

作者信息

Haas Kathryn L, Heemstra Jennifer M, Medema Marnix H, Charkoudian Louise K

机构信息

Department of Chemistry & Physics, Saint Mary's College , Notre Dame, Indiana 46556, United States.

Department of Chemistry, Emory University , Atlanta, Georgia 30322, United States.

出版信息

Biochemistry. 2018 Jan 30;57(4):383-389. doi: 10.1021/acs.biochem.7b00872. Epub 2017 Nov 2.

Abstract

Course-based undergraduate research experiences (CUREs) have gained traction as effective ways to expand the impact of undergraduate research while fulfilling pedagogical goals. In this Perspective, we present innovative ways to incorporate fundamental benefits and principles of CUREs into a classroom environment through information/technology-based research projects that lead to student-generated contributions to digital community resources (CoRes). These projects represent an attractive class of CUREs because they are less resource-intensive than laboratory-based CUREs, and the projects align with the expectations of today's students to create rapid and publicly accessible contributions to society. We provide a detailed discussion of two example types of CoRe projects that can be implemented in courses to impact research and education at the chemistry-biology interface: bioinformatics annotations and development of educational tools. Finally, we present current resources available for faculty interested in incorporating CUREs or CoRe projects into their pedagogical practices. In sharing these stories and resources, we hope to lower the barrier for widespread adoption of CURE and CoRe approaches and generate discussions about how to utilize the classroom experience to make a positive impact on our students and the future of the field of biochemistry.

摘要

基于课程的本科研究经历(CUREs)作为在实现教学目标的同时扩大本科研究影响力的有效方式,已受到广泛关注。在这篇观点文章中,我们介绍了一些创新方法,即通过基于信息/技术的研究项目,将CUREs的基本益处和原则融入课堂环境,这些项目能促使学生为数字社区资源(CoRes)做出贡献。这些项目是一类颇具吸引力的CUREs,因为它们比基于实验室的CUREs资源需求更少,并且符合当今学生对快速为社会做出公开可用贡献的期望。我们详细讨论了两种可在课程中实施的CoRe项目示例类型,它们能够在化学生物学交叉领域影响研究与教育:生物信息学注释和教育工具开发。最后,我们介绍了目前可供有兴趣将CUREs或CoRe项目纳入其教学实践的教师使用的资源。在分享这些案例和资源时,我们希望降低广泛采用CURE和CoRe方法的障碍,并引发关于如何利用课堂体验对我们的学生以及生物化学领域的未来产生积极影响 的讨论。

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Designing convergent chemistry curricula.设计融合化学课程。
Nat Chem Biol. 2016 May 18;12(6):382-6. doi: 10.1038/nchembio.2090.
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Minimum Information about a Biosynthetic Gene cluster.生物合成基因簇的最低信息要求
Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890.

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