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增加生物化学研究在本科教育中的可及性:苹果酸脱氢酶 CURE 社区。

Increasing access for biochemistry research in undergraduate education: The malate dehydrogenase CURE community.

机构信息

Chemistry and Biochemistry, University of San Diego, San Diego, California, USA.

出版信息

J Biol Chem. 2022 Sep;298(9):102298. doi: 10.1016/j.jbc.2022.102298. Epub 2022 Jul 31.

DOI:10.1016/j.jbc.2022.102298
PMID:35921892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9424567/
Abstract

Integrating research into the classroom environment is an influential pedagogical tool to support student learning, increase retention of STEM students, and help students identify as scientists. The evolution of course-based undergraduate research experiences (CUREs) has grown from individual faculty incorporating their research in the teaching laboratory into well-supported systems to sustain faculty engagement in CUREs. To support the growth of protein-centric biochemistry-related CUREs, we cultivated a community of enthusiastic faculty to develop and adopt malate dehydrogenase (MDH) as a CURE focal point. The MDH CURE Community has grown into a vibrant and exciting group of over 28 faculty from various institutions, including community colleges, minority-serving institutions, undergraduate institutions, and research-intensive institutions in just 4 years. This collective has also addressed important pedagogical questions on the impact of CURE collaboration and the length of the CURE experience in community colleges, undergraduate institutions, and research-intensive institutions. This work provided evidence that modular or partial-semester CUREs also support student outcomes, especially the positive impact it had on underrepresented students. We are currently focused on expanding the MDH CURE Community network by generating more teaching and research materials, creating regional hubs for local interaction and increasing mentoring capacity, and offering mentoring and professional development opportunities for new faculty adopters.

摘要

将研究融入课堂环境是一种有影响力的教学工具,可以支持学生学习,增加 STEM 学生的保留率,并帮助学生认同自己是科学家。基于课程的本科生研究经验 (CURE) 的发展已经从个别教师将他们的研究纳入教学实验室的模式,发展成为支持教师参与 CURE 的成熟系统。为了支持以蛋白质为中心的生物化学相关 CURE 的发展,我们培养了一批热情的教师,共同开发并采用苹果酸脱氢酶 (MDH) 作为 CURE 的重点。MDH CURE 社区在短短 4 年内已经发展成为一个由来自不同机构的 28 名教师组成的充满活力和令人兴奋的团体,这些机构包括社区学院、少数族裔服务机构、本科院校和研究密集型机构。这个集体还解决了关于 CURE 合作的影响以及 CURE 在社区学院、本科院校和研究密集型机构的经验长度的重要教学问题。这项工作提供了证据表明,模块化或半学期的 CURE 也支持学生的学习成果,特别是对代表性不足的学生的积极影响。我们目前的重点是通过生成更多的教学和研究材料、创建区域中心以促进本地互动和增加指导能力,以及为新的教师采用者提供指导和专业发展机会,来扩大 MDH CURE 社区网络。

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