Xu Yuyang, Chen Nan, Ma Aijia, Wang Zihuai, Zhang Yingyi, Liu Chengwu, Liu Lunxu
Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Western China Collaborative Innovation Center for Early Diagnosis and Multidisciplinary Therapy of Lung Cancer, Sichuan University, Chengdu, Sichuan, China.
Interact Cardiovasc Thorac Surg. 2017 Dec 1;25(6):862-871. doi: 10.1093/icvts/ivx219.
It remains unclear whether 3D systems are manoeuvrable in video-assisted thoracic surgery (VATS) for patients with thoracic diseases. The objective of this systematic review and meta-analysis was to evaluate the efficacy and safety of 3D VATS compared with 2D VATS.
A systemic research of the literature was performed using the PubMed, Embase, the Cochrane library, China National Knowledge Infrastructure, Wanfang and CQVIP databases through December 2016. Studies investigating the efficacy and safety of 3D VATS compared with 2D VATS were eligible for our meta-analysis. Odds ratios and mean differences or standard mean differences with 95% confidence intervals (95% CI) as well as a P-value were applied to compare continuous and dichotomous variables, respectively.
Seven studies with 1080 patients (525 patients for 3D VATS and 555 patients for 2D VATS) were included. There were significant differences in the 3D group with regard to shorter operation times (standard mean difference = -0.66, 95% CI: -0.98 to - 0.34; P < 0.001), less blood loss (mean difference = -12.12, 95% CI: -19.07 to - 5.16; P < 0.001) and shorter postoperative drainage times (standard mean difference = -0.53, 95% CI: -0.92 to - 0.14; P = 0.008) compared with the 2D group. However, no statistical difference was found for postoperative hospital stay, total postoperative drainage volume, postoperative drainage volume in 24 h, number of lymph nodes dissected and postoperative complications.
The results of this systematic review and meta-analysis suggest that 3D VATS might be an acceptable method for treating thoracic diseases in the future.
对于患有胸科疾病的患者,在电视辅助胸腔镜手术(VATS)中3D系统是否易于操作仍不明确。本系统评价和荟萃分析的目的是评估3D VATS与2D VATS相比的有效性和安全性。
通过检索PubMed、Embase、Cochrane图书馆、中国知网、万方和维普数据库,对截至2016年12月的文献进行系统研究。比较3D VATS与2D VATS有效性和安全性的研究符合我们的荟萃分析标准。分别应用比值比和均数差值或标准化均数差值及95%置信区间(95%CI)以及P值来比较连续变量和二分变量。
纳入了7项研究,共1080例患者(3D VATS组525例,2D VATS组555例)。3D组在手术时间较短(标准化均数差值=-0.66,95%CI:-0.98至-0.34;P<0.001)、失血较少(均数差值=-12.12,95%CI:-19.07至-5.16;P<0.001)和术后引流时间较短(标准化均数差值=-0.53,95%CI:-0.92至-0.14;P=0.008)方面与2D组存在显著差异。然而,在术后住院时间、术后总引流量、24小时引流量、清扫淋巴结数量和术后并发症方面未发现统计学差异。
本系统评价和荟萃分析结果表明,3D VATS未来可能是治疗胸科疾病的一种可接受的方法。