Rezaeian Ahmad
Department of Otorhinolaryngology, head and neck surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Am J Otolaryngol. 2018 Jan-Feb;39(1):10-13. doi: 10.1016/j.amjoto.2017.10.007. Epub 2017 Oct 10.
Nasal Polyposis is a benign tumor in nasal or paranasal mucosa, which confronts difficulties in management of healing after treatments with surgery. The aim of this study was to evaluate the effects of Spray Cryotherapy (SCT) on management of healing in patients with nasal polyposis who undergone functional endoscopic sinus surgery.
In this prospective, clinical trial study, we investigated on 40 patients with nasal polyposis that had indication for functional endoscopic sinus surgery. Patients were divided randomly into two parallel group; cryotherapy (with SCT) and placebo (without SCT). Evaluation of healing after surgery was evaluated with Lund-Mackay and The Sino-nasal outcome test (SNOT-22)-22 scores.
Postoperatively, Lund-Mackay and SNOT-22 scores were significantly decreased in both groups, however these scores were significantly lower in cryotherapy group in comparison with placebo group. Also there were no reported serious side effects in both groups.
In this paper, we concluded that usage of SCT is an effective and safe method on management of healing and develops recovery rates in patients with nasal polyposis undergoing functional endoscopic sinus surgery.
鼻息肉是鼻腔或鼻窦黏膜的一种良性肿瘤，手术治疗后愈合管理面临困难。本研究旨在评估喷雾冷冻疗法（SCT）对接受功能性鼻内镜鼻窦手术的鼻息肉患者愈合管理的效果。
在这项前瞻性临床试验研究中，我们调查了40例有功能性鼻内镜鼻窦手术指征的鼻息肉患者。患者被随机分为两个平行组：冷冻疗法（使用SCT）组和安慰剂（不使用SCT）组。术后愈合情况通过Lund-Mackay和鼻窦结局测试（SNOT-22）-22评分进行评估。
术后，两组的Lund-Mackay和SNOT-22评分均显著降低，但冷冻疗法组的这些评分与安慰剂组相比显著更低。两组均未报告严重副作用。
在本文中，我们得出结论，SCT的使用是一种有效且安全的愈合管理方法，可提高接受功能性鼻内镜鼻窦手术的鼻息肉患者的恢复率。
