[Blood lipids and the indicators of lipid peroxidation in patients with hemorrhagic fever with nephrotic syndrome].

Lipid peroxidation (LPO) was studied in 66 patients suffering from hemorrhagic fever with the renal syndrome (HFRS) by the results of determination of the content of malonic dialdehyde and acyl hydroperoxides in plasma. LPO intensity rose considerably, being the highest in a severe course of disease. LPO disorder developed against a background of considerable shifts in the level of total blood lipids and their fractions: cholesterol, total beta- and pre-beta-lipoproteins, total phospholipids and triglycerides. The author discussed the importance of LPO disorders revealed in HFRS pathogenesis and determination of the severity of disease and its prognosis.