Service de Parasitologie-Mycologie, CHRU, Lille, France; INSERM, U995-LIRIC, Fungal Associated Invasive & Inflammatory Diseases, F-59000 Lille, France.
Service de Parasitologie-Mycologie, CHRU, Lille, France.
Travel Med Infect Dis. 2017 Nov-Dec;20:26-30. doi: 10.1016/j.tmaid.2017.10.010. Epub 2017 Oct 16.
We describe a case of imported cutaneous gnathostomiasis in a Thai patient living in France. Gnathostomiasis is a zoonosis of food origin. The disease is endemic in Southeast Asia and Latin America. However, over the past 30 years, an increasing number of imported cases has been described in Europe and America. The disease is rare in Western Europe and the majority of cases described had a cutaneous clinical presentation. The disease may sometimes be confused with allergy, leading to a delay in diagnosis. Visceral symptoms are rare but may follow severe attacks. A definitive diagnosis can be obtained by the isolation of larvae from skin biopsies, but these are rarely performed. The diagnosis is usually presumptive, based on a combination of anamnestic, clinical, and biological factors. Several courses of the anti-helminths, albendazole or ivermectin, are often necessary. Although rare, the diagnosis should be evoked systematically in a migrant or traveller returning from an endemic area with cutaneous lesions.
我们描述了一名居住在法国的泰国患者的输入性皮肤颚口线虫病病例。颚口线虫病是一种食源性的动物源性疾病。该病在东南亚和拉丁美洲流行。然而，在过去的 30 年中，在欧美地区描述了越来越多的输入性病例。在西欧，该病较为罕见，大多数描述的病例均表现为皮肤临床症状。该病有时可能与过敏相混淆，导致诊断延迟。内脏症状较为罕见，但可能在严重发作后出现。通过从皮肤活检中分离幼虫可获得明确诊断，但很少进行此类检查。诊断通常是基于病史、临床和生物学因素的综合判断而做出的推测性诊断。通常需要几轮抗蠕虫药物（阿苯达唑或伊维菌素）治疗。尽管罕见，但对于从流行地区返回的移民或旅行者，如果出现皮肤损伤，应系统地进行这种诊断。
