Department of Nursing, Sugiyama Jogakuen University, 17-3, Hoshigaoka-motomachi, Chikusa-ku, Nagoya, 464-8662, Japan.
Nippon Sharyo, Ltd., 1-1, Sanbonmatsu-cho, Atsuta-ku, Nagoya, 456-8691, Japan.
Int J Public Health. 2018 Jan;63(1):49-55. doi: 10.1007/s00038-017-1043-9. Epub 2017 Oct 20.
This 3-year cohort study was conducted to investigate the relation between insomnia and development of depression in male workers, and to clarify the association between the severity of insomnia and the onset of depression.
Self-administered questionnaire surveys on depression and insomnia were conducted on male workers for 3 years. Depression was assessed with the Center for Epidemiologic Studies Depression Scale (CES-D), and insomnia was examined using the Athens Insomnia Scale (AIS). The analysis was done with 840 men who had no depression at baseline.
Depression symptoms were newly found in 113 men during this study. Cox regression analyses showed that people with insomnia (AIS score of ≥ 1) at baseline had about a 7 times greater risk for onset of depression. Furthermore, compared with those with AIS score of 0 (no insomnia), people with AIS score of 1-3 had a 5.2-fold greater risk of depression and those with a score of 4 or higher indicated about tenfold greater risk.
A new finding was that the risk for onset of depression increased with the severity of insomnia.
本为期 3 年的队列研究旨在探讨男性工人中失眠与抑郁发展之间的关系，并阐明失眠严重程度与抑郁发病之间的关联。
对男性工人进行了为期 3 年的抑郁和失眠自我管理问卷调查。使用流行病学研究中心抑郁量表（CES-D）评估抑郁，使用雅典失眠量表（AIS）评估失眠。对基线时无抑郁的 840 名男性进行了分析。
在这项研究中，有 113 名男性新出现了抑郁症状。Cox 回归分析显示，基线时存在失眠（AIS 评分≥1）的人患抑郁的风险约增加 7 倍。此外，与 AIS 评分为 0（无失眠）的人相比，AIS 评分为 1-3 的人患抑郁的风险增加 5.2 倍，而 AIS 评分达到或更高的人则表明风险增加了约 10 倍。
一个新发现是，抑郁发病的风险随着失眠严重程度的增加而增加。
