Bayliss Christopher D, Booth Karen L, Williams Robin, Dark John H, Gould Kate F
Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
Ann Thorac Surg. 2017 Nov;104(5):e379-e381. doi: 10.1016/j.athoracsur.2017.07.005.
Pneumococcal mycotic aneurysms are rare and associated with significant mortality and morbidity. Early intravenous antibiotic therapy and surgical intervention is the mainstay of treatment. Pneumococci frequently autolyze in blood cultures, making microbiological diagnosis challenging. We present the case of a man in his mid 70s with multiple thoracoabdominal mycotic aneurysms. Surgery was performed to a threatening saccular aortic arch aneurysm. Samples were sent for microbiological analysis and all were culture negative. The samples were then referred for bacterial 16S ribosomal RNA sequencing, which revealed evidence of infection with Streptococcus pneumoniae.
肺炎球菌性霉菌性动脉瘤较为罕见，且与较高的死亡率和发病率相关。早期静脉应用抗生素治疗和手术干预是主要的治疗方法。肺炎球菌在血培养中常发生自溶，这使得微生物学诊断具有挑战性。我们在此报告一例70多岁男性伴有多发胸腹霉菌性动脉瘤的病例。对一个有破裂风险的囊状主动脉弓动脉瘤进行了手术。采集样本进行微生物学分析，所有培养结果均为阴性。随后将样本送去进行细菌16S核糖体RNA测序，结果显示有肺炎链球菌感染的证据。
