Department of Diagnostic and Interventional Radiology, Adnan Menderes University, Aydın, Turkey.
Department of Infectious Diseases and Clinical Microbiology, Adnan Menderes University, Aydın, Turkey.
J Chin Med Assoc. 2018 Jun;81(6):565-570. doi: 10.1016/j.jcma.2017.09.006. Epub 2017 Oct 19.
The aim of this study was to investigate atherosclerotic load at the lower extremity in patients with diabetic foot and charcot neuro-arthropathy and compare them with patients with diabetic foot without charcot neuro-arthropathy.
This retrospective study consists of 78 patients with diabetic foot who had lower extremity angiography with antegrade approach. All patients were classified into two groups; neuro ischemic wounds with charcot neuro-arthropathy (30/78) and without charcot neuro-arthropathy (48/78).Atherosclerotic load at the side of diabetic foot was determined by using the Bollinger angiogram scoring method. Comparison of atherosclerotic load between the two groups was performed.
The mean of total and infrapopliteal level angiogram scoring of all patients was 33.3 (standard deviation, sd:±17.2) and 29.3 (sd:±15.6), respectively. The mean of total and infrapopliteal level angiogram scoring of neuroischemic wounds with charcot neuro-arthropathy group was 18.1 (sd:±11.6) and 15.7 (sd:±10.4), respectively. The mean of total and infrapopliteal level angiogram scoring of neuroischemic wounds without charcot neuro-arthropathy group was 42.8 (sd:±12.7) and 37.7 (sd:±12.0), respectively. There was a statistically significant difference between the two groups of mean total and infrapopliteal angiogram scoring (p < 0.01).
This angiographic study confirms that the atherosclerotic load in patients with diabetic foot and chronic charcot neuro-arthropathy is significantly less than in patients with neuroischemic diabetic foot wounds without chronic charcot neuro-arthropathy.
本研究旨在探讨糖尿病足伴夏科氏神经关节病患者下肢的动脉粥样硬化负荷，并与无夏科氏神经关节病的糖尿病足患者进行比较。
本回顾性研究纳入了 78 例行顺行下肢血管造影的糖尿病足患者。所有患者均分为两组：伴有夏科氏神经关节病的神经缺血性创面（30/78 例）和不伴有夏科氏神经关节病的神经缺血性创面（48/78 例）。采用 Bollinger 血管造影评分法确定糖尿病足侧的动脉粥样硬化负荷，并比较两组间的动脉粥样硬化负荷。
所有患者的总血管造影评分和膝下血管造影评分的平均值分别为 33.3（标准差，sd：±17.2）和 29.3（sd：±15.6）。伴有夏科氏神经关节病的神经缺血性创面组的总血管造影评分和膝下血管造影评分的平均值分别为 18.1（sd：±11.6）和 15.7（sd：±10.4）。不伴有夏科氏神经关节病的神经缺血性创面组的总血管造影评分和膝下血管造影评分的平均值分别为 42.8（sd：±12.7）和 37.7（sd：±12.0）。两组的总血管造影评分和膝下血管造影评分均存在统计学差异（p<0.01）。
本血管造影研究证实，糖尿病足伴慢性夏科氏神经关节病患者的动脉粥样硬化负荷明显低于无慢性夏科氏神经关节病的糖尿病足神经缺血性创面患者。
