Park Jung E
Department of Neurology, Dongguk University Ilsan Hospital, Goyang, Korea.
J Clin Neurol. 2017 Oct;13(4):317-324. doi: 10.3988/jcn.2017.13.4.317.
Praxis, the ability to perform skilled or learned movements is essential for daily living. Inability to perform such praxis movements is defined as apraxia. Apraxia can be further classified into subtypes such as ideomotor, ideational and limb-kinetic apraxia. Relevant brain regions have been found to include the motor, premotor, temporal and parietal cortices. Apraxia is found in a variety of highly prevalent neurological disorders including dementia, stroke and Parkinsonism. Furthermore, apraxia has been shown to negatively affect quality of life. Therefore, recognition and treatment of this disorder is critical. This article provides an overview of apraxia and highlights studies dealing with the neurophysiology of this disorder, opening up novel perspectives for the use of motor training and noninvasive brain stimulation as treatment.
实践能力,即执行熟练或习得动作的能力,对日常生活至关重要。无法执行此类实践动作被定义为失用症。失用症可进一步细分为观念运动性、观念性和肢体运动性失用症等亚型。已发现相关脑区包括运动皮层、运动前区皮层、颞叶和顶叶皮层。失用症见于多种高发性神经系统疾病,包括痴呆、中风和帕金森病。此外,失用症已被证明会对生活质量产生负面影响。因此,识别和治疗这种疾病至关重要。本文概述了失用症,并重点介绍了有关该疾病神经生理学的研究,为将运动训练和非侵入性脑刺激用作治疗方法开辟了新的视角。