Timár J, Smirnova E A, Lapis K
Vopr Onkol. 1988;34(12):1439-42.
Immunohistochemistry is finding an ever increasing application for electron microscopic diagnosis of human viral diseases. Certain progress has been made in the use of peroxidase-DAB/OsO4 as an electron-dense marker, and colloid gold. The paper discusses immunohistochemistry application for electron microscopic detection of such lymphotropic viruses as VSV (virus of vesicular stomatitis cultured in mink's lung cells), HTLV-1 (virus of human T4-cell C91Pl lymphoma culture) and HTLV-III/HIV-1 (virus growing in human T4-cell H9 culture).
免疫组织化学在人类病毒性疾病的电子显微镜诊断中的应用越来越广泛。在使用过氧化物酶-DAB/OsO4作为电子致密标记物以及胶体金方面已经取得了一定进展。本文讨论了免疫组织化学在电子显微镜检测诸如水泡性口炎病毒（在貂肺细胞中培养）、人类T4细胞白血病病毒1型（在人类T4细胞C91Pl淋巴瘤培养物中）以及人类嗜T淋巴细胞病毒III型/艾滋病病毒1型（在人类T4细胞H9培养物中生长）等嗜淋巴细胞病毒中的应用。
