McGill University, Montreal, QC, H3A 0G4, Canada.
Phys Med Biol. 2017 Nov 21;62(24):9240-9259. doi: 10.1088/1361-6560/aa954c.
A formalism has been proposed for small and non-standard photon fields in which [Formula: see text] correction factors are used to correct dosimeter response in small fields (indiviual or composite) relative to that in a larger machine-specific reference (MSR) field. For clinical plans consisting of several fields, a plan-class specific reference (PCSR) plan can also be defined, serving as an intermediate calibration field between the MSR and clinical plans within a certain plan-class. In this work, the formalism was applied in the calculation of [Formula: see text] for 21 clinical plans delivered by the [Formula: see text] radiosurgery system, each plan employing one or two of the smallest diameter collimators: 5 mm, 7.5 mm, and 10 mm. Three detectors were considered: the Exradin A16 and A26 micro chambers, and the W1 plastic scintillator. The clinical plans were grouped into 7 plan-classes according to commonly shared characteristics. The suitability of using a PCSR plan to represent the detector response of each plan within the plan-class was investigated. Total and intermediate correction factors were calculated using the [Formula: see text] Monte Carlo user code. The corrections for the micro chambers were large, primarily due to the presence of the low-density air cavity and the volume averaging effect. The correction for the scintillator was found to be close to unity for most plans, indicating that this detector may be used to measure small clinical plan correction factors in any plan except for those using the 5 mm collimator. The PCSR plan was shown to be applicable to plan-classes comprising isocentric plans only, with plan-classes divided according to collimator size. For non-isocentric plans, the variation of [Formula: see text] as a function of the point of measurement within a single plan, as well as the high inter-plan-class variability of the correction factor, precludes the use of a PCSR plan.
已经提出了一种适用于小尺寸和非标准光子场的形式主义,其中使用[公式:见正文]校正因子来校正小尺寸(单个或组合)与较大机器特定参考(MSR)场中的剂量计响应。对于由多个场组成的临床计划,也可以定义计划类别特定参考(PCSR)计划,作为 MSR 和临床计划之间的中间校准场,属于某个计划类别。在这项工作中,形式主义被应用于 21 个由[公式:见正文]伽玛刀系统提供的临床计划的[公式:见正文]的计算,每个计划使用一个或两个最小直径准直器:5mm、7.5mm 和 10mm。考虑了三种探测器:Exradin A16 和 A26 微室,以及 W1 塑料闪烁体。根据共同的特征,临床计划被分为 7 个计划类别。研究了使用 PCSR 计划来代表计划类别内每个计划的探测器响应的适用性。使用[公式:见正文]Monte Carlo 用户代码计算总校正和中间校正因子。微室的校正因子很大,主要是由于低密度空气腔和体积平均效应的存在。对于大多数计划,发现闪烁体的校正因子接近 1,这表明该探测器可用于测量任何计划(除了使用 5mm 准直器的计划)中的小临床计划校正因子。结果表明,PCSR 计划仅适用于等中心计划的计划类别,根据准直器尺寸对计划类别进行划分。对于非等中心计划,[公式:见正文]作为单个计划内测量点的函数的变化,以及校正因子的高计划类别间可变性,排除了 PCSR 计划的使用。