Dorsey Tovah I, Rozanski Elizabeth A, Sharp Claire R, Babyak Jonathan M, de Laforcade Armelle M
Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA (Dorsey, Rozanski, Babyak, de Laforcade).
College of Veterinary Medicine, School of Veterinary and Life Sciences, Murdoch, Australia (Sharp).
J Vet Diagn Invest. 2018 Jan;30(1):165-168. doi: 10.1177/1040638717737349. Epub 2017 Oct 23.
We investigated the effect of pyometra on kaolin-activated thromboelastography (TEG). Eighteen client-owned dogs with pyometra and 8 healthy spayed dogs were recruited. TEG parameters and packed cell volume were determined. Results from spayed females and from intact females with pyometra were compared using a Student t-test and Wilcoxon rank sum test. Bitches with pyometra were hypercoagulable compared to spayed bitches as evidenced by elevated maximum amplitude, G, and alpha angle. There were no significant group differences in R time, K time, or clot lysis at 30 or 60 min. Dogs with pyometra should be anticipated to have hypercoagulable TEG variables, and this should be addressed when planning surgical and medical therapy.
我们研究了子宫蓄脓对高岭土激活血栓弹力图(TEG)的影响。招募了18只患有子宫蓄脓的客户拥有犬和8只健康的绝育犬。测定了TEG参数和红细胞压积。使用学生t检验和威尔科克森秩和检验比较了绝育雌性犬和患有子宫蓄脓的未绝育雌性犬的结果。与绝育母犬相比,患有子宫蓄脓的母犬具有高凝状态,表现为最大振幅、G值和α角升高。在R时间、K时间或30分钟或60分钟时的血凝块溶解方面,两组之间没有显著差异。患有子宫蓄脓的犬预计会有高凝的TEG变量,在计划手术和药物治疗时应考虑到这一点。