使用高性能电阻抗断层成像系统对猪肺区域空气分布进行成像。

Imaging of regional air distributions in porcine lungs using high-performance electrical impedance tomography system.

作者信息

Jang G Y, Kim Y B, Wi H, Oh T I, Chung C R, Suh G Y, Woo E J

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul;2017:349-351. doi: 10.1109/EMBC.2017.8036834.

DOI:10.1109/EMBC.2017.8036834

Abstract

Electrical impedance tomography (EIT) allows functional imaging of regional lung ventilation for real-time bedside monitoring of mechanically ventilated patients. Images showing time-changes of regional air distributions in the lungs can provide valuable diagnostic information for lung protective mechanical ventilation. This paper reports in vivo porcine imaging experiments of regional lung ventilation using a 16-channel parallel EIT system. Real-time time-difference chest images of 10 animals were reconstructed during mechanical ventilations with a temporal resolution of 50 frame/s. Analyzing the images together with the airway volume-pressure information from the mechanical ventilator, we could successfully produce regional compliance images at PEEP (positive end expiratory pressure) titration. From in vivo animal experiments, we propose the method as a continuous monitoring means for LPV (lung protective ventilation).

摘要

电阻抗断层成像（EIT）可对区域肺通气进行功能成像，用于对机械通气患者进行实时床边监测。显示肺部区域空气分布随时间变化的图像可为肺保护性机械通气提供有价值的诊断信息。本文报道了使用16通道并行EIT系统对区域肺通气进行的猪体内成像实验。在机械通气期间，以50帧/秒的时间分辨率重建了10只动物的实时时差胸部图像。将这些图像与来自机械通气机的气道容积-压力信息一起分析，我们能够在呼气末正压（PEEP）滴定过程中成功生成区域顺应性图像。通过体内动物实验，我们提出该方法可作为肺保护性通气（LPV）的连续监测手段。