Meroni Davide, Maglioli Camilla Carpano, Bovio Dario, Greco Francesco G, Aliverti Andrea
Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul;2017:1385-1388. doi: 10.1109/EMBC.2017.8037091.
Electrical Impedance Tomography (EIT) is an image reconstruction technique applied in medicine for the electrical imaging of living tissues. In literature there is the evidence that a large resistivity variation related to the differences of the human tissues exists. As a result of this interest for the electrical characterization of the biological samples, recently the attention is also focused on the identification and characterization of the human tissue, by studying the homogeneity of its structure. An 8 electrodes needle-probe device has been developed with the intent of identifying the structural inhomogeneities under the surface layers. Ex-vivo impeditivity measurements, by placing the needle-probe in 5 different patterns of fat and lean porcine tissue, were performed, and impeditivity maps were obtained by EIDORS open source software for image reconstruction in electrical impedance. The values composing the maps have been analyzed, pointing out a good tissue discrimination, and the conformity with the real images. We conclude that this device is able to perform impeditivity maps matching to reality for position and orientation. In all the five patterns presented is possible to identify and replicate correctly the heterogeneous tissue under test. This new procedure can be helpful to the medical staff to completely characterize the biological sample, in different unclear situations.
电阻抗断层成像（EIT）是一种应用于医学领域的图像重建技术，用于对活体组织进行电阻抗成像。文献表明，人体组织之间存在与电阻率差异相关的显著变化。由于对生物样本的电阻抗特性的关注，近来人们也通过研究人体组织结构的均匀性，将注意力集中在人体组织的识别和特性表征上。为了识别表层下的结构不均匀性，开发了一种8电极针式探头装置。通过将针式探头以5种不同模式放置在猪的脂肪组织和瘦肉组织中进行了体外阻抗测量，并使用EIDORS开源软件进行电阻抗图像重建，从而获得了阻抗图。对组成这些图的值进行了分析，结果表明该装置具有良好的组织分辨能力，并且与实际图像相符。我们得出结论，该装置能够生成与实际位置和方向相匹配的阻抗图。在所呈现的所有5种模式中，都能够正确识别和复制被测的异质组织。这种新方法有助于医护人员在不同的不明情况下全面表征生物样本。
