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用于可穿戴医疗应用的同时采集心电图(ECG)和光电容积脉搏波(PPG)的生物信号集成电路。

Biosignal integrated circuit with simultaneous acquisition of ECG and PPG for wearable healthcare applications.

作者信息

Kim Hyungseup, Park Yunjong, Ko Youngwoon, Mun Yeongjin, Lee Sangmin, Ko Hyoungho

机构信息

Department of Electronics Engineering, Chungnam National University, Daejeon, Korea.

Department of Biomedical Engineering, Kyung Hee University, Yongin, Korea.

出版信息

Technol Health Care. 2018;26(1):3-9. doi: 10.3233/THC-171401.

Abstract

BACKGROUND

Wearable healthcare systems require measurements from electrocardiograms (ECGs) and photoplethysmograms (PPGs), and the blood pressure of the user. The pulse transit time (PTT) can be calculated by measuring the ECG and PPG simultaneously. Continuous-time blood pressure without using an air cuff can be estimated by using the PTT.

OBJECTIVE

This paper presents a biosignal acquisition integrated circuit (IC) that can simultaneously measure the ECG and PPG for wearable healthcare applications.

METHODS

Included in this biosignal acquisition circuit are a voltage mode instrumentation amplifier (IA) for ECG acquisition and a current mode transimpedance amplifier for PPG acquisition. The analog outputs from the ECG and PPG channels are muxed and converted to digital signals using 12-bit successive approximation register (SAR) analog-to-digital converter (ADC).

RESULTS

The proposed IC is fabricated by using a standard 0.18 μm CMOS process with an active area of 14.44 mm2. The total current consumption for the multichannel IC is 327 μA with a 3.3 V supply. The measured input referred noise of ECG readout channel is 1.3 μVRMS with a bandwidth of 0.5 Hz to 100 Hz. And the measured input referred current noise of the PPG readout channel is 0.122 nA/√Hz with a bandwidth of 0.5 Hz to 100 Hz.

CONCLUSIONS

The proposed IC, which is implemented using various circuit techniques, can measure ECG and PPG signals simultaneously to calculate the PTT for wearable healthcare applications.

摘要

背景

可穿戴医疗系统需要测量心电图(ECG)、光电容积脉搏波图(PPG)以及用户的血压。脉搏传输时间(PTT)可通过同时测量ECG和PPG来计算。利用PTT可估计不使用气袖带的连续血压。

目的

本文介绍一种用于可穿戴医疗应用的生物信号采集集成电路(IC),该电路可同时测量ECG和PPG。

方法

该生物信号采集电路包括用于采集ECG的电压模式仪表放大器(IA)和用于采集PPG的电流模式跨阻放大器。ECG和PPG通道的模拟输出经多路复用,并使用12位逐次逼近寄存器(SAR)模数转换器(ADC)转换为数字信号。

结果

所提出的IC采用标准0.18μm CMOS工艺制造,有源面积为14.44mm²。该多通道IC在3.3V电源供电下的总功耗为327μA。测得的ECG读出通道的输入参考噪声为1.3μVRMS,带宽为0.5Hz至100Hz。测得的PPG读出通道的输入参考电流噪声为0.122nA/√Hz,带宽为0.5Hz至100Hz。

结论

所提出的IC采用多种电路技术实现,可同时测量ECG和PPG信号,以计算用于可穿戴医疗应用的PTT。

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