Youn Gun Jung, Chung Woo Chul, Lee Ji Min, Paik Chang Nyol, Oh Jung Hwan, Jung Sung Hoon
Division of Gastroenterology, Department of Internal Medicine, St. Vincent Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
Division of Gastroenterology, Department of Internal Medicine, St. Paul's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Korean J Gastroenterol. 2017 Oct 25;70(4):190-197. doi: 10.4166/kjg.2017.70.4.190.
BACKGROUND/AIMS: In recent years, the incidence of acute pancreatitis (AP) has been increasing. A better understanding of the etiology is directly linked to more favorable outcomes. Unfortunately, there have been reports suggesting the variation of etiologies of AP across countries. The objective of this study was to determine the etiology of AP in a general hospital of Seoul-Gyeonggi province in Korea during the past decade.
We retrospectively reviewed the medical records of consecutive patients with AP who were admitted to St. Paul's Hospital (Seoul, Korea) with an affiliation to the Catholic University of Korea between January 2003 and January 2013.
A total of 1,110 patients were enrolled, totaling 1,833 attacks, and the most frequent cause of AP was alcohol consumption. The recurrence rate of AP was 24.5% (272/1,110), and habitual recurrence rate (more than three times) was 12.6% (140/1,110). The rate of severe AP was 4.9% (90/1,833 attacks). The mortality rate of AP was 2.6% (29/1,110 patients). The frequency of an idiopathic cause of AP was 13.3%. The recurrence rate and mortality rate of idiopathic AP were 16.2% and 5.4%, respectively. In 41.7% (10/24) of cases of idiopathic AP, microlithiasis was suspected.
Between 2003 and 2013 in Korea, alcohol was the most frequent cause of AP in the general hospital of Seoul-Gyeonggi province of Korea. It appears that alcohol abstinence program may be necessary. Further nationwide studies would be needed to evaluate the etiologies of AP.
背景/目的：近年来，急性胰腺炎（AP）的发病率一直在上升。更好地了解病因直接关系到更良好的治疗结果。不幸的是，有报告表明各国AP的病因存在差异。本研究的目的是确定过去十年韩国首尔-京畿道一家综合医院中AP的病因。
我们回顾性分析了2003年1月至2013年1月期间入住韩国天主教大学附属圣保罗医院（韩国首尔）的连续性AP患者的病历。
共纳入1110例患者，发作1833次，AP最常见的病因是饮酒。AP的复发率为24.5%（272/1110），习惯性复发率（超过三次）为12.6%（140/1110）。重症AP的发生率为4.9%（90/1833次发作）。AP的死亡率为2.6%（29/1110例患者）。AP特发性病因的发生率为13.3%。特发性AP的复发率和死亡率分别为16.2%和5.4%。在41.7%（10/24）的特发性AP病例中怀疑有微结石症。
2003年至2013年期间在韩国，饮酒是韩国首尔-京畿道综合医院中AP最常见的病因。似乎有必要开展戒酒项目。需要进一步开展全国性研究以评估AP的病因。
