Liu Y, Tang H F, Ning Z, Zheng H, He N, Zhang Y Y
Putuo District Center for Disease Control and Prevention, Shanghai 200333, China; School of Public Health, The Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai 200032, China.
Putuo District Center for Disease Control and Prevention, Shanghai 200333, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Oct 10;38(10):1363-1366. doi: 10.3760/cma.j.issn.0254-6450.2017.10.013.
To understand the prevalence rates of HIV-syphilis and HIV-herpes simplex virus 2 (HSV-2) co-infections and related factors among men having sex with men (MSM) who had visited the voluntary HIV counseling and testing (VCT) clinics in Shanghai, China. 756 eligible MSM who attended the VCT clinics of Shanghai Municipality and Putuo district during March to August, 2015 were recruited to participate in a cross-sectional survey with questionnaire interview and blood testing for HIV, syphilis and HSV-2. A total of 732 participants completed a valid questionnaire survey. The prevalence rates were 3.3 (24/732) for HIV/Syphilis co-infection, 1.9 (14/732) for HIV/HSV-2 co-infection, and 0.7 (5/732) for HIV/Syphilis/HSV-2 co-infection, respectively. HIV prevalence appeared significantly higher among syphilis-infected participants (45.3, 24/53) than those without Syphilis (7.2, 61/679) (χ(2)=63.11, <0.001), and was also significantly higher among HSV-2 infected participants (34.1, 14/41) than those without the HSV-2 infection (10.3, 71/691) (χ(2)=21.49, <0.001). Results from the Multivariate regression analysis indicated that participants who were migrants (=3.50, 95: 1.01-12.17), having had middle school or lower levels of education (=4.46, 95: 1.54-12.87) or ever used illicit drugs (=4.25, 95: 1.67-10.82, =0.002) were under possible risks on HIV and Syphilis co-infection. Those participants who had high middle school or lower levels of education (=6.87, 95: 1.86-25.42; =9.82, 95: 2.25-42.85) were under risk on HIV and HSV-2 co-infection. HIV/Syphilis and HIV/HSV-2 co-infection were seen among MSM who attended the VCT clinics in Shanghai that called for special attention, especially on migrants, those with low education or illicit drug users.
为了解在中国上海自愿接受艾滋病咨询检测（VCT）门诊就诊的男男性行为者（MSM）中，艾滋病毒与梅毒、艾滋病毒与单纯疱疹病毒2型（HSV-2）合并感染的患病率及相关因素。2015年3月至8月期间，招募了756名符合条件、在上海市和普陀区VCT门诊就诊的MSM，参与一项横断面调查，进行问卷调查以及艾滋病毒、梅毒和HSV-2的血液检测。共有732名参与者完成了有效的问卷调查。艾滋病毒/梅毒合并感染的患病率为3.3%（24/732），艾滋病毒/HSV-2合并感染的患病率为1.9%（14/732），艾滋病毒/梅毒/HSV-2合并感染的患病率为0.7%（5/732）。梅毒感染参与者中的艾滋病毒患病率（45.3%，24/53）显著高于未感染梅毒者（7.2%，61/679）（χ(2)=63.11，<0.001），HSV-２感染参与者中的艾滋病毒患病率（34.1%，14/41）也显著高于未感染HSV-2者（10.3%，71/691）（χ(2)=21.49，<0.001）。多因素回归分析结果表明，移民参与者（比值比=3.50，95%可信区间：1.01-12.17）、初中及以下文化程度者（比值比=4.46，95%可信区间：1.54-12.87）或曾使用过非法药物者（比值比=4.25，95%可信区间：1.67-10.82，P=0.002）感染艾滋病毒和梅毒的风险可能更高。高中及以下文化程度者感染艾滋病毒和HSV-2的风险更高（比值比=6.87，95%可信区间：1.86-25.42；P=9.82，95%可信区间：2.25-42.85）。在上海VCT门诊就诊的MSM中发现了艾滋病毒/梅毒和艾滋病毒/HSV-2合并感染情况，这需要特别关注，尤其是移民、文化程度低者或非法药物使用者。
