Zimbudzi Edward, Lo Clement, Ranasinha Sanjeeva, Fulcher Gregory R, Jan Stephen, Kerr Peter G, Polkinghorne Kevan R, Russell Grant, Walker Rowan G, Zoungas Sophia
School of Public Health and Preventive Medicine, Monash Centre for Health Research and Implementation (MCHRI), Monash University, Melbourne, Victoria, Australia.
Department of Nephrology, Monash Health, Melbourne, Victoria, Australia.
BMJ Open. 2017 Oct 22;7(10):e017695. doi: 10.1136/bmjopen-2017-017695.
To evaluate the extent of patient activation and factors associated with activation in adults with comorbid diabetes and chronic kidney disease (CKD).
A cross-sectional study.
Renal/diabetes clinics of four tertiary hospitals across the two largest states of Australia.
Adult patients (over 18 years) with comorbid diabetes and CKD (estimated glomerular filtration rate <60 mL/min/1.73 m).
Patients completed the Patient Activation Measure, the Kidney Disease Quality of Life and demographic and clinical data survey from January to December 2014. Factors associated with patient activation were examined using χ or t-tests and linear regression.
Three hundred and five patients with median age of 68 (IQR 14.8) years were studied. They were evenly distributed across socioeconomic groups, stage of kidney disease and duration of diabetes but not gender. Approximately 46% reported low activation. In patients with low activation, the symptom/problem list, burden of kidney disease subscale and mental composite subscale scores were all significantly lower (all p<0.05). On multivariable analysis, factors associated with lower activation for all patients were older age, worse self-reported health in the burden of kidney disease subscale and lower self-care scores. Additionally, in men, worse self-reported health in the mental composite subscale was associated with lower activation and in women, worse self-reported health scores in the symptom problem list and greater renal impairment were associated with lower activation.
Findings from this study suggest that levels of activation are low in patients with diabetes and CKD. Older age and worse self-reported health were associated with lower activation. This data may serve as the basis for the development of interventions needed to enhance activation and outcomes for patients with diabetes and CKD.
评估合并糖尿病和慢性肾脏病(CKD)的成人患者的患者激活程度及与激活相关的因素。
一项横断面研究。
澳大利亚两个最大州的四家三级医院的肾脏/糖尿病诊所。
合并糖尿病和CKD(估计肾小球滤过率<60 mL/min/1.73 m²)的成年患者(18岁以上)。
患者于2014年1月至12月完成患者激活量表、肾脏病生活质量以及人口统计学和临床数据调查。使用χ²检验或t检验以及线性回归分析与患者激活相关的因素。
对305例中位年龄为68岁(四分位间距14.8岁)的患者进行了研究。他们在社会经济群体、肾脏疾病分期和糖尿病病程方面分布均匀,但在性别上分布不均。约46%的患者报告激活程度低。在激活程度低的患者中,症状/问题清单、肾脏病负担子量表和心理综合子量表得分均显著较低(均p<0.05)。多变量分析显示,所有患者激活程度较低的相关因素包括年龄较大、在肾脏病负担子量表中自我报告的健康状况较差以及自我护理得分较低。此外,在男性中,心理综合子量表中自我报告的健康状况较差与激活程度较低相关;在女性中,症状问题清单中自我报告的健康得分较差以及肾功能损害较重与激活程度较低相关。
本研究结果表明,糖尿病和CKD患者的激活水平较低。年龄较大和自我报告的健康状况较差与激活程度较低相关。这些数据可为制定提高糖尿病和CKD患者激活程度及改善预后所需的干预措施提供依据。