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奶牛乳腺炎疫苗:最新进展与应用建议

Mastitis vaccines in dairy cows: Recent developments and recommendations of application.

作者信息

Ismail Zuhair Bani

机构信息

Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22100, Jordan.

出版信息

Vet World. 2017 Sep;10(9):1057-1062. doi: 10.14202/vetworld.2017.1057-1062. Epub 2017 Sep 12.

DOI:10.14202/vetworld.2017.1057-1062
PMID:29062194
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5639103/
Abstract

The objective of this review article was to summarize the most recent clinical field trials that have been published evaluating the use of different types of vaccines against mastitis pathogens in dairy cows. Mastitis is one of the most common and economically important diseases in dairy cows in the world. The disease is considered an important welfare issue facing the dairy industry in addition to the loss of production and premature removal or death of affected cows. Losses are also related to high cost of veterinary medicines and the cost of unsalable milk of treated cows. Mastitis can be caused by either contagious or environmental pathogens both of which are best prevented rather than treated. In addition to the application of best management practices in the parlor during milking, vaccination against common udder pathogens is widely practiced in many dairy farms to prevent or reduce the severity of clinical mastitis. In this review, the most recent clinical field studies that evaluated the use of different types of vaccines in dairy cows are summarized.

摘要

这篇综述文章的目的是总结已发表的最新临床田间试验,这些试验评估了不同类型疫苗在奶牛乳腺炎病原体防治中的应用。乳腺炎是世界范围内奶牛最常见且在经济上最重要的疾病之一。除了产奶量损失以及患病奶牛过早被淘汰或死亡外,该疾病还被视为奶牛养殖业面临的一个重要福利问题。损失还与兽药的高成本以及患病奶牛无法销售的牛奶成本有关。乳腺炎可由传染性病原体或环境病原体引起,这两种病原体最好是预防而非治疗。除了在挤奶厅实施最佳管理措施外,许多奶牛场还广泛采用针对常见乳房病原体的疫苗接种来预防或减轻临床乳腺炎的严重程度。在这篇综述中,总结了评估不同类型疫苗在奶牛中应用的最新临床田间研究。

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Immune response after an experimental intramammary challenge with killed Staphylococcus aureus in cows and heifers vaccinated and not vaccinated with Startvac, a polyvalent mastitis vaccine.在奶牛和小母牛中,用多价乳腺炎疫苗Startvac进行免疫接种和未进行免疫接种的情况下,经实验性乳房内注射灭活金黄色葡萄球菌后的免疫反应。
J Dairy Sci. 2017 Jan;100(1):769-782. doi: 10.3168/jds.2016-11269. Epub 2016 Nov 3.
2
Mastitis vaccination using a commercial polyvalent vaccine or a herd-specific Staphylococcus aureus vaccine. Results of a controlled field trial on a dairy farm.使用商业多价疫苗或特定牛群的金黄色葡萄球菌疫苗进行乳腺炎疫苗接种。奶牛场对照田间试验结果。
Tierarztl Prax Ausg G Grosstiere Nutztiere. 2016 Aug 17;44(4):219-29. doi: 10.15653/TPG-150912. Epub 2016 Jun 29.
3
Vaccination against Staphylococcus aureus mastitis in two Swedish dairy herds.瑞典两个奶牛场针对金黄色葡萄球菌性乳腺炎的疫苗接种
Acta Vet Scand. 2015 Nov 25;57:81. doi: 10.1186/s13028-015-0171-6.
4
An investigation of the efficacy of a polyvalent mastitis vaccine using different vaccination regimens under field conditions in the United Kingdom.在英国实地条件下,采用不同免疫方案对一种多价乳腺炎疫苗的效力进行的一项调查。
J Dairy Sci. 2015 Mar;98(3):1706-20. doi: 10.3168/jds.2014-8332. Epub 2014 Dec 18.
5
Efficacy of vaccination on Staphylococcus aureus and coagulase-negative staphylococci intramammary infection dynamics in 2 dairy herds.疫苗接种对两个奶牛场金黄色葡萄球菌和凝固酶阴性葡萄球菌乳房内感染动态的影响
J Dairy Sci. 2014;97(8):5250-64. doi: 10.3168/jds.2014-8008. Epub 2014 Jun 2.
6
Update on control of Staphylococcus aureus and Streptococcus agalactiae for management of mastitis.金黄色葡萄球菌和无乳链球菌控制更新:用于乳腺炎管理。
Vet Clin North Am Food Anim Pract. 2012 Jul;28(2):203-16. doi: 10.1016/j.cvfa.2012.03.010. Epub 2012 Apr 17.
7
Economic consequences of mastitis and withdrawal of milk with high somatic cell count in Swedish dairy herds.瑞典奶牛群中乳腺炎及体细胞数高的牛奶拒收的经济后果。
Animal. 2010 Oct;4(10):1758-70. doi: 10.1017/S1751731110000704.
8
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9
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Vet Microbiol. 2011 Mar 24;148(2-4):117-24. doi: 10.1016/j.vetmic.2010.10.003. Epub 2010 Nov 5.