Tay Wei Lin, Loh Wann Jia, Lee Lianne Ai Ling, Chng Chiaw Ling
Department of Endocrinology, Singapore General Hospital, Singapore, Singapore.
Department of Endocrinology, Changi General Hospital, Singapore, Singapore.
Endocrinol Diabetes Metab Case Rep. 2017 Oct 13;2017. doi: 10.1530/EDM-17-0109. eCollection 2017.
We report a patient with Graves' disease who remained persistently hyperthyroid after a total thyroidectomy and also developed Graves' ophthalmopathy 5 months after surgery. She was subsequently found to have a mature cystic teratoma containing struma ovarii after undergoing a total hysterectomy and salpingo-oophorectomy for an incidental ovarian lesion.
It is important to investigate for other causes of primary hyperthyroidism when thyrotoxicosis persists after total thyroidectomy.TSH receptor antibody may persist after total thyroidectomy and may potentially contribute to the development of Graves' ophthalmopathy.
我们报告一例格雷夫斯病患者,该患者在全甲状腺切除术后仍持续甲亢,且术后5个月出现格雷夫斯眼病。她在因偶然发现的卵巢病变接受全子宫切除及输卵管卵巢切除术后,被发现有一个含有卵巢甲状腺肿的成熟囊性畸胎瘤。
全甲状腺切除术后若仍存在甲状腺毒症,调查原发性甲亢的其他病因很重要。促甲状腺激素受体抗体在全甲状腺切除术后可能持续存在,并可能促使格雷夫斯眼病的发生。